USP21 Antibody (3D10): sc-293400
- USP21 Antibody (3D10) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 100 µg/ml
- raised against amino acids 466-565 of USP21 of human origin
- recommended for detection of USP21 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for USP21 Antibody (3D10). This work is in progress.
USP21 Antibody (3D10) is a mouse monoclonal IgG2a antibody that detects USP21 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). USP21, also known as ubiquitin specific peptidase 21, is a 565 amino acid protein that plays a crucial role in the ubiquitin pathway, which is essential for regulating various intracellular processes, including signal transduction and transcriptional activation. USP21 is primarily located in the cytoplasm and nucleus, where USP21 exerts its function by removing ubiquitin from ubiquitinated proteins, thereby influencing protein stability and degradation. USP21′s ability to modulate the levels of ubiquitin and NEDD8-conjugated proteins is vital for maintaining cellular homeostasis and responding to stress signals. Additionally, USP21 interacts with several specific proteins, including p53 and NF-κB, which are key regulators of cell cycle and apoptosis, highlighting USP21′s importance in cancer biology and therapeutic interventions. With multiple isoforms arising from alternative splicing, USP21′s diverse functions underscore its significance in cellular regulation and potential as a target for drug development.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
USP21 Antibody (3D10) | sc-293400 | 100 µg/ml | $316.00 |