Twinfilin-2 Antibody (F-2): sc-514305
- Twinfilin-2 Antibody (F-2) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 176-235 mapping within an internal region of Twinfilin-2 of human origin
- recommended for detection of Twinfilin-2 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Twinfilin-2 Antibody (F-2) for WB applications. These reagents are now offered in bundles with Twinfilin-2 Antibody (F-2) (see ordering information below).
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Twinfilin-2 Antibody (F-2) is a mouse monoclonal IgG1 antibody that detects Twinfilin-2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Twinfilin-2, also known as TWF2, A6r, A6RP, or PTK9L, is a 349 amino acid protein that plays a crucial role in regulating actin dynamics within cells. Twinfilin-2 is primarily located in the perinuclear region of the cytoplasm and cytoskeleton, where anti-Twinfilin-2 antibody (F-2) shows binding to this actin-binding protein. Twinfilin-2 binds and sequesters G-actin, while also capping barbed ends of actin filaments, which inhibits actin polymerization and is essential for various actin-related motile and morphological processes. Twinfilin-2′s function is crucial for cellular activities such as cell migration, shape maintenance, and response to external stimuli. Twinfilin-2 undergoes post-translational modifications, including phosphorylation by protein kinase C zeta, which can influence activity and interactions with other proteins. The gene encoding Twinfilin-2 is located on human chromosome 3, a region containing over 1,100 genes, including those associated with chemokine receptors and various cancer-related loci, highlighting potential implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Twinfilin-2 Antibody (F-2) | sc-514305 | 200 µg/ml | $322.00 | |||
Twinfilin-2 Antibody (F-2): m-IgG Fc BP-HRP Bundle | sc-538621 | 200 µg Ab; 10 µg BP | $361.00 | |||
Twinfilin-2 Antibody (F-2): m-IgGκ BP-HRP Bundle | sc-536266 | 200 µg Ab; 40 µg BP | $361.00 | |||
Twinfilin-2 Antibody (F-2): m-IgG1 BP-HRP Bundle | sc-545796 | 200 µg Ab; 20 µg BP | $361.00 |