Twinfilin-1 Antibody (C-12): sc-376418
- Twinfilin-1 Antibody (C-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 175-236 mapping near the C-terminus of Twinfilin-1 of human origin
- recommended for detection of Twinfilin-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Twinfilin-1 Antibody (C-12) for WB and IHC(P) applications. These reagents are now offered in bundles with Twinfilin-1 Antibody (C-12) (see ordering information below).
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Twinfilin-1 Antibody (C-12) is a mouse monoclonal IgG1 antibody that detects Twinfilin-1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Twinfilin-1 is a crucial actin monomer-binding protein that plays a significant role in regulating cytoskeletal dynamics, which is essential for numerous cellular processes such as cell motility, shape maintenance, and division. Twinfilin-1 is primarily located in the cytoplasm, where Twinfilin-1 interacts with actin filaments to prevent their assembly by sequestering actin monomers and inhibiting nucleotide exchange. Proper functioning of Twinfilin-1 is vital, as dysregulation can lead to various cellular dysfunctions and has been implicated in diseases such as cancer and neurodegenerative disorders. Additionally, Twinfilin-1′s activity is modulated by post-translational modifications, including phosphorylation, which can influence binding affinity and localization within the cell. Anti-Twinfilin-1 antibody (C-12) specifically targets Twinfilin-1, making this monoclonal antibody an invaluable tool for researchers studying cytoskeletal regulation and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Twinfilin-1 Antibody (C-12) | sc-376418 | 200 µg/ml | $322.00 | |||
Twinfilin-1 Antibody (C-12): m-IgG Fc BP-HRP Bundle | sc-537984 | 200 µg Ab; 10 µg BP | $361.00 | |||
Twinfilin-1 Antibody (C-12): m-IgGκ BP-HRP Bundle | sc-535486 | 200 µg Ab; 40 µg BP | $361.00 | |||
Twinfilin-1 Antibody (C-12): m-IgG1 BP-HRP Bundle | sc-545475 | 200 µg Ab; 20 µg BP | $361.00 |