TTC12 Antibody (C-9): sc-393493
- TTC12 Antibody (C-9) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 56-79 near the N-terminus of TTC12 of human origin
- recommended for detection of TTC12 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TTC12 Antibody (C-9) for WB applications. These reagents are now offered in bundles with TTC12 Antibody (C-9) (see ordering information below).
TTC12 Antibody (C-9) is a mouse monoclonal IgG1 antibody that detects TTC12 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TTC12, also known as TPARM, is a 705 amino acid cytoplasmic protein characterized by tetratricopeptide repeat domain and three armadillo repeat motifs, which play a crucial role in mediating protein-protein interactions essential for various cellular pathways. The presence of TPR motif allows TTC12 to engage in specific interactions with other proteins, influencing processes such as cell signaling and gene regulation. TTC12 is expressed in several tissues, including testis, prostate, lung, and various cancer types, such as neuroblastoma and colon cancer. TTC12 gene is located on human chromosome 11, a region frequently deleted in numerous cancers, highlighting potential role as a tumor suppressor gene. TTC12′s ability to interact with specific proteins may provide insights into function in tumorigenesis and cellular homeostasis, making anti-TTC12 antibody (C-9) a valuable tool for researchers studying these critical biological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TTC12 Antibody (C-9) References:
- Identification and characterization of human FOXN5 and rat Foxn5 genes in silico. | Katoh, M. and Katoh, M. 2004. Int J Oncol. 24: 1339-44. PMID: 15067358
- Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples. | Yang, BZ., et al. 2007. Hum Mol Genet. 16: 2844-53. PMID: 17761687
- In vivo differentiation and genomic evolution in adult male germ cell tumors. | Korkola, JE., et al. 2008. Genes Chromosomes Cancer. 47: 43-55. PMID: 17943972
- Influence of DRD2 and ANKK1 genotypes on apomorphine-induced growth hormone (GH) response in alcohol-dependent patients. | Lucht, M., et al. 2010. Prog Neuropsychopharmacol Biol Psychiatry. 34: 45-9. PMID: 19796663
- Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortium. | McGuire, V., et al. 2011. J Neurol Sci. 307: 22-9. PMID: 21663922
- Further replication of the synergistic interaction between LPHN3 and the NTAD gene cluster on ADHD and its clinical course throughout adulthood. | Kappel, DB., et al. 2017. Prog Neuropsychopharmacol Biol Psychiatry. 79: 120-127. PMID: 28624582
- Ankyrin Repeat and Kinase Domain Containing 1 Gene, and Addiction Vulnerability. | Koeneke, A., et al. 2020. Int J Mol Sci. 21: PMID: 32260442
- Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans. | Kimbrel, NA., et al. 2023. JAMA Psychiatry. 80: 135-145. PMID: 36515925
- Obesity impairs ciliary function and mucociliary clearance in the murine airway epithelium. | Tanaka, Y., et al. 2024. Am J Physiol Lung Cell Mol Physiol. 327: L406-L414. PMID: 39104315
- Transcriptomic imputation identifies tissue-specific genes associated with cervical myelopathy. | Seah, C., et al. 2025. Spine J. 25: 588-596. PMID: 39491753
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TTC12 Antibody (C-9) | sc-393493 | 200 µg/ml | $316.00 | |||
TTC12 Antibody (C-9): m-IgG Fc BP-HRP Bundle | sc-538231 | 200 µg Ab; 10 µg BP | $354.00 | |||
TTC12 Antibody (C-9): m-IgGκ BP-HRP Bundle | sc-535801 | 200 µg Ab; 40 µg BP | $354.00 | |||
TTC12 Antibody (C-9): m-IgG1 BP-HRP Bundle | sc-545592 | 200 µg Ab; 20 µg BP | $354.00 | |||
TTC12 (C-9) Neutralizing Peptide | sc-393493 P | 100 µg/0.5 ml | $68.00 |