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Trophinin Antibody (A-6): sc-393834

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Datasheets
  • Trophinin Antibody (A-6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 1-24 at the N-terminus of Trophinin of mouse origin
  • Trophinin Antibody (A-6) is recommended for detection of Trophinin of mouse origin by WB, IP, IF and ELISA
  • Anti-Trophinin Antibody (A-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Trophinin Antibody (A-6) for WB applications. These reagents are now offered in bundles with Trophinin Antibody (A-6) (see ordering information below).
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    Trophinin Antibody (A-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects Trophinin of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Trophinin antibody (A-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Trophinin, also referred to as TRO or MAGED3, is a crucial apical cell adhesion molecule that plays a significant role in forming a complex with Bystin and Tastin, essential for cell adhesion and embryo implantation. Trophinin is predominantly located in chorionic villi trophoblasts and maternal endometrial epithelial cells, with expression dependent on implantation. Trophinin mediates cell adhesion through homophilic Trophinin-Trophinin binding, vital for successful embryo attachment to the uterine lining. Trophinin expression is induced by Choriogonadotropin β and interleukin-1 beta, and elevated Trophinin levels enhance cell adhesion, suggesting that promoting Trophinin expression could improve implantation rates. Trophinin is also present in macrophages and features one MAGE (melanoma-associated antigen) domain, highlighting potential involvement in immune responses and cancer biology.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Trophinin Antibody (A-6)

    sc-393834
    200 µg/ml
    $322.00

    Trophinin Antibody (A-6): m-IgG Fc BP-HRP Bundle

    sc-530597
    200 µg Ab; 10 µg BP
    $361.00

    Trophinin Antibody (A-6): m-IgGκ BP-HRP Bundle

    sc-524111
    200 µg Ab, 40 µg BP
    $361.00

    Trophinin Antibody (A-6): m-IgG1 BP-HRP Bundle

    sc-544154
    200 µg Ab; 20 µg BP
    $361.00

    Trophinin Antibody (A-6) AC

    sc-393834 AC
    500 µg/ml, 25% agarose
    $424.00

    Trophinin Antibody (A-6) HRP

    sc-393834 HRP
    200 µg/ml
    $322.00

    Trophinin Antibody (A-6) FITC

    sc-393834 FITC
    200 µg/ml
    $336.00

    Trophinin Antibody (A-6) PE

    sc-393834 PE
    200 µg/ml
    $349.00

    Trophinin Antibody (A-6) Alexa Fluor® 488

    sc-393834 AF488
    200 µg/ml
    $364.00

    Trophinin Antibody (A-6) Alexa Fluor® 546

    sc-393834 AF546
    200 µg/ml
    $364.00

    Trophinin Antibody (A-6) Alexa Fluor® 594

    sc-393834 AF594
    200 µg/ml
    $364.00

    Trophinin Antibody (A-6) Alexa Fluor® 647

    sc-393834 AF647
    200 µg/ml
    $364.00

    Trophinin Antibody (A-6) Alexa Fluor® 680

    sc-393834 AF680
    200 µg/ml
    $364.00

    Trophinin Antibody (A-6) Alexa Fluor® 790

    sc-393834 AF790
    200 µg/ml
    $364.00

    Trophinin (A-6) Neutralizing Peptide

    sc-393834 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-393834 P appropriate for?

    Asked by: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Great Western blot data of Trophinin expressionGreat Western blot data of Trophinin expression in mouse brain tissue extract. -SCBT QC
    Date published: 2013-09-03
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    Trophinin Antibody (A-6) is rated 5.0 out of 5 by 1.
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