TRMT112 Antibody (F-7): sc-398481
- TRMT112 Antibody (F-7) is a mouse monoclonal IgG2a κ TRMT112 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 20-118 mapping within an internal region of TRMT112 of human origin
- TRMT112 Antibody (F-7) is recommended for detection of TRMT112 of human origin by WB, IP, IF and ELISA
- Anti-TRMT112 Antibody (F-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TRMT112 Antibody (F-7) for WB applications. These reagents are now offered in bundles with TRMT112 Antibody (F-7) (see ordering information below).
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TRMT112 Antibody (F-7) is a mouse monoclonal IgG2a kappa light chain antibody that detects TRMT112 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TRMT112 (F-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. TRMT112 plays a crucial role in the modification of tRNA, specifically in the methylation of the wobble position of tRNA, which is essential for accurate protein synthesis and cellular function. This post-translational modification influences the stability and efficiency of tRNA, thereby impacting the overall translation process and protein expression levels within the cell. Dysregulation of TRMT112 has been implicated in various diseases, highlighting TRMT112′s importance in maintaining cellular homeostasis and the potential consequences of dysfunction. With approximately 135 million base pairs and 1,400 genes, chromosome 11, where TRMT112 is encoded, is known for its dense association with gene and disease links, further underscoring anti-TRMT112 antibody (F-7)′s significance in research and clinical applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TRMT112 Antibody (F-7) References:
- The 11q terminal deletion disorder: a prospective study of 110 cases. | Grossfeld, PD., et al. 2004. Am J Med Genet A. 129A: 51-61. PMID: 15266616
- Human chromosome 11 DNA sequence and analysis including novel gene identification. | Taylor, TD., et al. 2006. Nature. 440: 497-500. PMID: 16554811
- KCNQ1 K+ channel-mediated cardiac channelopathies. | Loussouarn, G., et al. 2006. Methods Mol Biol. 337: 167-83. PMID: 16929947
- Skipping of Exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome. | Zehelein, J., et al. 2006. J Biol Chem. 281: 35397-403. PMID: 16987820
- Beta-thalassaemia and sickle cell anaemia as paradigms of hypercoagulability. | Ataga, KI., et al. 2007. Br J Haematol. 139: 3-13. PMID: 17854302
- The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3. | Berger, AC., et al. 2007. J Cell Sci. 120: 3640-52. PMID: 17895371
- Wilms tumour: prognostic factors, staging, therapy and late effects. | Kaste, SC., et al. 2008. Pediatr Radiol. 38: 2-17. PMID: 18026723
- Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. | Lee, JH. and Paull, TT. 2007. Oncogene. 26: 7741-8. PMID: 18066086
- Targeted cancer therapies based on the inhibition of DNA strand break repair. | O'Connor, MJ., et al. 2007. Oncogene. 26: 7816-24. PMID: 18066095
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRMT112 Antibody (F-7) | sc-398481 | 200 µg/ml | $322.00 | |||
TRMT112 Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-530816 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRMT112 Antibody (F-7): m-IgGκ BP-HRP Bundle | sc-524361 | 200 µg Ab, 40 µg BP | $361.00 | |||
TRMT112 Antibody (F-7): m-IgG2a BP-HRP Bundle | sc-547598 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRMT112 Antibody (F-7) AC | sc-398481 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TRMT112 Antibody (F-7) HRP | sc-398481 HRP | 200 µg/ml | $322.00 | |||
TRMT112 Antibody (F-7) FITC | sc-398481 FITC | 200 µg/ml | $336.00 | |||
TRMT112 Antibody (F-7) PE | sc-398481 PE | 200 µg/ml | $349.00 | |||
TRMT112 Antibody (F-7) Alexa Fluor® 488 | sc-398481 AF488 | 200 µg/ml | $364.00 | |||
TRMT112 Antibody (F-7) Alexa Fluor® 546 | sc-398481 AF546 | 200 µg/ml | $364.00 | |||
TRMT112 Antibody (F-7) Alexa Fluor® 594 | sc-398481 AF594 | 200 µg/ml | $364.00 | |||
TRMT112 Antibody (F-7) Alexa Fluor® 647 | sc-398481 AF647 | 200 µg/ml | $364.00 | |||
TRMT112 Antibody (F-7) Alexa Fluor® 680 | sc-398481 AF680 | 200 µg/ml | $364.00 | |||
TRMT112 Antibody (F-7) Alexa Fluor® 790 | sc-398481 AF790 | 200 µg/ml | $364.00 |