Trimethyl Histone H4 Antibody (6F8-D9): sc-134216
- Trimethyl Histone H4 Antibody (6F8-D9) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against a short amino acid sequence containing trimethylated lysine 20 of Lys 20 trimethylated Histone H4 of human origin
- Anti-Trimethyl Histone H4 Antibody (6F8-D9) is recommended for detection of Lys 20 trimethylated Histone H4 of mouse, rat and human origin by WB, IP and ELISA; may cross-react with lysine 20 dimethylated Histone H4; non cross-reactive with Histone H3
- Anti-Trimethyl Histone H4 Antibody (6F8-D9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Trimethyl Histone H4 Antibody (6F8-D9) for WB applications. These reagents are now offered in bundles with Trimethyl Histone H4 Antibody (6F8-D9) (see ordering information below).
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SEE ALSO...
Trimethyl Histone H4 Antibody (6F8-D9) is a mouse monoclonal IgG1 kappa light chain antibody that detects Lys 20 trimethylated Histone H4 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Trimethyl Histone H4 (6F8-D9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Histone H4 plays a crucial role in the structural organization of chromatin as a key component of the nucleosome, which is the fundamental unit of chromatin. The nucleosome consists of an octamer formed by two copies each of the core histones H2A, H2B, H3, and H4, wrapping approximately 146 base pairs of DNA. This structural arrangement is vital for DNA packaging within the nucleus and influences gene expression regulation. The post-translational modification of histones, including the trimethylation of Lys 20 on Histone H4, is essential for various cellular processes, such as DNA repair, replication, and transcriptional regulation, as these modifications can alter chromatin structure and accessibility. Anti-Trimethyl Histone H4 antibody (6F8-D9) specifically recognizes this modification, making this antibody an invaluable tool for researchers studying epigenetic regulation and chromatin dynamics in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Trimethyl Histone H4 Antibody (6F8-D9) | sc-134216 | 200 µg/ml | $322.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9): m-IgG Fc BP-HRP Bundle | sc-528787 | 200 µg Ab; 10 µg BP | $361.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9): m-IgGκ BP-HRP Bundle | sc-521295 | 200 µg Ab, 40 µg BP | $361.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9): m-IgG1 BP-HRP Bundle | sc-543130 | 200 µg Ab; 20 µg BP | $361.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) AC | sc-134216 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) HRP | sc-134216 HRP | 200 µg/ml | $322.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) FITC | sc-134216 FITC | 200 µg/ml | $336.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) PE | sc-134216 PE | 200 µg/ml | $349.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) Alexa Fluor® 488 | sc-134216 AF488 | 200 µg/ml | $364.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) Alexa Fluor® 546 | sc-134216 AF546 | 200 µg/ml | $364.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) Alexa Fluor® 594 | sc-134216 AF594 | 200 µg/ml | $364.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) Alexa Fluor® 647 | sc-134216 AF647 | 200 µg/ml | $364.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) Alexa Fluor® 680 | sc-134216 AF680 | 200 µg/ml | $364.00 | |||
Trimethyl Histone H4 Antibody (6F8-D9) Alexa Fluor® 790 | sc-134216 AF790 | 200 µg/ml | $364.00 |