TRIM52 Antibody (A-4): sc-398954
- TRIM52 Antibody (A-4) is a mouse monoclonal IgG2b κ TRIM52 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 79-124 mapping within an internal region of TRIM52 of human origin
- TRIM52 Antibody (A-4) is recommended for detection of TRIM52 of human origin by WB, IP, IF and ELISA
- Anti-TRIM52 Antibody (A-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TRIM52 Antibody (A-4) for WB applications. These reagents are now offered in bundles with TRIM52 Antibody (A-4) (see ordering information below).
TRIM52 Antibody (A-4) is a mouse monoclonal IgG2b kappa light chain antibody that detects TRIM52 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-TRIM52 antibody (A-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TRIM52, also known as RNF102, is a 297 amino acid member of the tripartite motif (TRIM) family, characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, and a RING finger. TRIM52 plays a crucial role in cellular processes such as protein ubiquitination, which is essential for regulating protein degradation and maintaining cellular homeostasis. The ubiquitination pathway is vital for various cellular functions, including cell cycle regulation, DNA repair, and response to stress, making TRIM52 an important player in maintaining cellular integrity and function. The gene encoding TRIM52 is located on chromosome 5, which is associated with several genetic disorders, including Cockayne syndrome and familial adenomatous polyposis, highlighting the significance of TRIM52 in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TRIM52 Antibody (A-4) References:
- Recent advances in myelodysplastic syndromes. | Shadduck, RK., et al. 2007. Exp Hematol. 35: 137-43. PMID: 17379099
- Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias. | Falini, B., et al. 2007. Haematologica. 92: 519-32. PMID: 17488663
- Fetal trisomy 5 mosaicism: case report and literature review. | Villa, N., et al. 2007. Am J Med Genet A. 143A: 2343-6. PMID: 17702005
- Chromosome 5q subtelomeric deletion syndrome. | Rauch, A. and Dörr, HG. 2007. Am J Med Genet C Semin Med Genet. 145C: 372-6. PMID: 17910075
- Two cases of deletion 5p syndrome: one with paternal involvement and another with atypical presentation. | Azman, BZ., et al. 2008. Singapore Med J. 49: e98-e100. PMID: 18418516
- Speech and language development in cri du chat syndrome: a critical review. | Kristoffersen, KE. 2008. Clin Linguist Phon. 22: 443-57. PMID: 18484284
- Mapping of 5q35 chromosomal rearrangements within a genomically unstable region. | Buysse, K., et al. 2008. J Med Genet. 45: 672-8. PMID: 18628311
- Revealing the pathogenesis of the 5q- syndrome. | Valent, P. 2008. Eur J Clin Invest. 38: 539-40. PMID: 18717823
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRIM52 Antibody (A-4) | sc-398954 | 200 µg/ml | $322.00 | |||
TRIM52 Antibody (A-4): m-IgG Fc BP-HRP Bundle | sc-530988 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRIM52 Antibody (A-4): m-IgGκ BP-HRP Bundle | sc-524556 | 200 µg Ab, 40 µg BP | $361.00 | |||
TRIM52 Antibody (A-4): m-IgG2b BP-HRP Bundle | sc-550246 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRIM52 Antibody (A-4) AC | sc-398954 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TRIM52 Antibody (A-4) HRP | sc-398954 HRP | 200 µg/ml | $322.00 | |||
TRIM52 Antibody (A-4) FITC | sc-398954 FITC | 200 µg/ml | $336.00 | |||
TRIM52 Antibody (A-4) PE | sc-398954 PE | 200 µg/ml | $349.00 | |||
TRIM52 Antibody (A-4) Alexa Fluor® 488 | sc-398954 AF488 | 200 µg/ml | $364.00 | |||
TRIM52 Antibody (A-4) Alexa Fluor® 546 | sc-398954 AF546 | 200 µg/ml | $364.00 | |||
TRIM52 Antibody (A-4) Alexa Fluor® 594 | sc-398954 AF594 | 200 µg/ml | $364.00 | |||
TRIM52 Antibody (A-4) Alexa Fluor® 647 | sc-398954 AF647 | 200 µg/ml | $364.00 | |||
TRIM52 Antibody (A-4) Alexa Fluor® 680 | sc-398954 AF680 | 200 µg/ml | $364.00 | |||
TRIM52 Antibody (A-4) Alexa Fluor® 790 | sc-398954 AF790 | 200 µg/ml | $364.00 |