TMEM205 Antibody (G-1): sc-390447
- TMEM205 Antibody (G-1) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 129-144 within an internal region of TMEM205 of human origin
- recommended for detection of TMEM205 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TMEM205 Antibody (G-1) for WB applications. These reagents are now offered in bundles with TMEM205 Antibody (G-1) (see ordering information below).
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SEE ALSO...
TMEM205 Antibody (G-1) is a mouse monoclonal IgG2b antibody that detects TMEM205 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TMEM205 is a 189 amino acid transmembrane protein predominantly expressed in the liver, pancreas, and adrenal glands, playing a crucial role in cellular signaling and potentially influencing drug resistance in cancer therapy. Notably, TMEM205 has been implicated in the development of cisplatin resistance, as elevated levels of TMEM205 in conjunction with Rab 8 may hinder the efficacy of this potent platinum-based anti-neoplastic agent, which operates by forming DNA adducts that trigger apoptosis. Understanding the function of TMEM205 is vital, as TMEM205 may serve as a biomarker or therapeutic target in cancer chemotherapy, providing insights into overcoming resistance mechanisms. The TMEM205 gene is located on human chromosome 19, a region that encompasses approximately 63 million bases and contains over 1,400 genes, representing more than 2% of the human genome. With diverse applications and significant biological implications, anti-TMEM205 antibody (G-1) is an essential tool for researchers investigating the complexities of cancer treatment and cellular responses.
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Contains Mercury: All HRP conjugates (including bundle forms) contain thiomersal, a mercury compound. Do not dispose in trash. Dispose as hazardous chemical waste according to local, state and federal regulations.
Download thiomersal SDS
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMEM205 Antibody (G-1) | sc-390447 | 200 µg/ml | $322.00 | |||
TMEM205 Antibody (G-1): m-IgGκ BP-HRP Bundle | sc-535621 | 200 µg Ab; 40 µg BP | $361.00 | |||
TMEM205 Antibody (G-1): m-IgG2b BP-HRP Bundle | sc-549458 | 200 µg Ab; 10 µg BP | $361.00 | |||
TMEM205 (G-1) Neutralizing Peptide | sc-390447 P | 100 µg/0.5 ml | $69.00 |