TLR10 Antibody (2A11): sc-293300

TLR10 Antibody (2A11) is a mouse monoclonal IgG1 kappa light chain antibody that detects TLR10 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-TLR10 antibody (2A11) is available as non-conjugated format. TLR10 plays a crucial role in the immune system as a member of the Toll-like receptor family, essential for recognizing pathogens and initiating immune responses. TLR10 modulates immune response by influencing pro-inflammatory cytokine and chemokine production, significantly regulating inflammation and adaptive immunity development. TLR10 expression predominantly occurs in immune-related tissues such as spleen, lymph nodes, thymus, and tonsils, highlighting TLR10′s importance in immune surveillance and response. TLR10′s interaction with various ligands and close relationship with other TLRs, such as TLR1 and TLR6, underscores TLR10′s potential as a therapeutic target in immune-related diseases. TLR10 (2A11) antibody enables valuable insights into immune regulation mechanisms and TLR roles in host defense.

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TLR10 Antibody (2A11) References:

1. TLR6: A novel member of an expanding toll-like receptor family.  |  Takeuchi, O., et al. 1999. Gene. 231: 59-65. PMID: 10231569
2. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors.  |  Brightbill, HD., et al. 1999. Science. 285: 732-6. PMID: 10426995
3. Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells.  |  Chuang, T. and Ulevitch, RJ. 2001. Biochim Biophys Acta. 1518: 157-61. PMID: 11267672
4. Drosophila Toll and IL-1 receptor.  |  Gay, NJ. and Keith, FJ. 1991. Nature. 351: 355-6. PMID: 1851964
5. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity.  |  Medzhitov, R., et al. 1997. Nature. 388: 394-7. PMID: 9237759
6. A family of human receptors structurally related to Drosophila Toll.  |  Rock, FL., et al. 1998. Proc Natl Acad Sci U S A. 95: 588-93. PMID: 9435236

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-TLR10 Antibody (2A11) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-TLR10 Antibody (2A11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

TLR10 Antibody (2A11) Specifications

Alternate Product Name: TLR10

Product Clone Name: 2A11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-811

Epitope Target: TLR10

Epitope Species: human

Product Reactivity/Detection: TLR10

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for TLR10 Antibody (2A11): N/A