TLE1 Antibody (C-7): sc-137097
- TLE1 Antibody (C-7) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 200-350 of TLE1 of mouse origin
- recommended for detection of TLE1 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-137097 X, 200 µg/0.1 ml)
- See TLE1 (F-4): sc-137098 for TLE1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG1 BP-HRP is the preferred secondary detection reagent for TLE1 Antibody (C-7) for WB applications. This reagent is now offered in a bundle with TLE1 Antibody (C-7) (see ordering information below).
TLE1 Antibody (C-7) is a mouse monoclonal IgG1 antibody that detects TLE1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TLE1, a member of the transducin-like enhancer of split (TLE) gene family, plays a crucial role in the regulation of gene expression during cellular differentiation and development. TLE1 functions primarily as a transcriptional repressor, interacting with various transcription factors to modulate their activity, which is essential for processes such as neurogenesis and epithelial differentiation. TLE1 is involved in the regulation of the CSF1 receptor through interaction with AML1, highlighting TLE1′s importance in hematopoiesis and immune responses. TLE1 expression is particularly significant in cervical squamous metaplasias and carcinomas, where TLE1 is upregulated, suggesting potential use as a biomarker for these conditions. Additionally, TLE1′s dynamic expression pattern during cell differentiation underscores TLE1′s importance in the transition of cells from an immature to a differentiated state, making TLE1 a valuable target for research in developmental biology and cancer studies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TLE1 Antibody (C-7) | sc-137097 | 200 µg/ml | $322.00 | |||
TLE1 Antibody (C-7): m-IgG1 BP-HRP Bundle | sc-542649 | 200 µg Ab; 20 µg BP | $361.00 | |||
TLE1 Antibody (C-7) X | sc-137097 X | 200 µg/0.1 ml | $322.00 |