TIP120B Antibody (H-7): sc-515406
- TIP120B Antibody (H-7) is a mouse monoclonal IgG1 κ TIP120B antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 726-748 within an internal region of TIP120B of human origin
- TIP120B Antibody (H-7) is recommended for detection of TIP120B of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TIP120B Antibody (H-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TIP120B Antibody (H-7) for WB applications. These reagents are now offered in bundles with TIP120B Antibody (H-7) (see ordering information below).
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TIP120B Antibody (H-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects TIP120B protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-TIP120B antibody (H-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TIP120B plays a crucial role in transcriptional regulation, specifically as a TBP-interacting protein that enhances the activity of the TATA-binding protein (TBP). This interaction is vital because TBP is a key component of the transcription machinery, necessary for the assembly of the preinitiation complex and the recruitment of RNA polymerase II, which is essential for the transcription of protein-coding genes. TIP120B is predominantly expressed in muscle tissues, distinguishing itself from TIP120A, which is more widely expressed. The unique expression pattern of TIP120B suggests specialized functions in muscle gene regulation, potentially influencing muscle development and function. Using TIP120B (H-7) monoclonal antibody in research can provide insights into the mechanisms of transcriptional regulation and the specific roles of TIP120B in muscle biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TIP120B Antibody (H-7) References:
- TIP120B: a novel TIP120-family protein that is expressed specifically in muscle tissues. | Aoki, T., et al. 1999. Biochem Biophys Res Commun. 261: 911-6. PMID: 10441524
- TATA-Binding protein-interacting protein 120, TIP120, stimulates three classes of eukaryotic transcription via a unique mechanism. | Makino, Y., et al. 1999. Mol Cell Biol. 19: 7951-60. PMID: 10567521
- Advances in RNA polymerase II transcription. | Zawel, L. and Reinberg, D. 1992. Curr Opin Cell Biol. 4: 488-95. PMID: 1497921
- General initiation factors for RNA polymerase II. | Conaway, RC. and Conaway, JW. 1993. Annu Rev Biochem. 62: 161-90. PMID: 8352588
- The role of general initiation factors in transcription by RNA polymerase II. | Roeder, RG. 1996. Trends Biochem Sci. 21: 327-35. PMID: 8870495
- Molecular cloning of a novel 120-kDa TBP-interacting protein. | Yogosawa, S., et al. 1996. Biochem Biophys Res Commun. 229: 612-7. PMID: 8954946
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TIP120B Antibody (H-7) | sc-515406 | 200 µg/ml | $322.00 | |||
TIP120B Antibody (H-7): m-IgG Fc BP-HRP Bundle | sc-531354 | 200 µg Ab; 10 µg BP | $361.00 | |||
TIP120B Antibody (H-7): m-IgGκ BP-HRP Bundle | sc-525025 | 200 µg Ab, 40 µg BP | $361.00 | |||
TIP120B Antibody (H-7): m-IgG1 BP-HRP Bundle | sc-544501 | 200 µg Ab; 20 µg BP | $361.00 | |||
TIP120B Antibody (H-7) AC | sc-515406 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TIP120B Antibody (H-7) HRP | sc-515406 HRP | 200 µg/ml | $322.00 | |||
TIP120B Antibody (H-7) FITC | sc-515406 FITC | 200 µg/ml | $336.00 | |||
TIP120B Antibody (H-7) PE | sc-515406 PE | 200 µg/ml | $349.00 | |||
TIP120B Antibody (H-7) Alexa Fluor® 488 | sc-515406 AF488 | 200 µg/ml | $364.00 | |||
TIP120B Antibody (H-7) Alexa Fluor® 546 | sc-515406 AF546 | 200 µg/ml | $364.00 | |||
TIP120B Antibody (H-7) Alexa Fluor® 594 | sc-515406 AF594 | 200 µg/ml | $364.00 | |||
TIP120B Antibody (H-7) Alexa Fluor® 647 | sc-515406 AF647 | 200 µg/ml | $364.00 | |||
TIP120B Antibody (H-7) Alexa Fluor® 680 | sc-515406 AF680 | 200 µg/ml | $364.00 | |||
TIP120B Antibody (H-7) Alexa Fluor® 790 | sc-515406 AF790 | 200 µg/ml | $364.00 | |||
TIP120B (H-7) Neutralizing Peptide | sc-515406 P | 100 µg/0.5 ml | $69.00 |