Thrombospondin 1 Antibody (MS-421): sc-81755
- Thrombospondin 1 Antibody (MS-421) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against reduced and alkylated Thrombospondin 1 of human origin
- recommended for detection of reduced and non-reduced Thrombospondin 1 of mouse, rat, human, equine, bovine and porcine origin by WB, IP, IF and IHC(P)
- See Thrombospondin 1 (C-8): sc-393504 for Thrombospondin 1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Thrombospondin 1 Antibody (MS-421) for WB and IHC(P) applications. This reagent is now offered in a bundle with Thrombospondin 1 Antibody (MS-421) (see ordering information below).
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Thrombospondin 1 Antibody (MS-421) is a mouse monoclonal IgG1 kappa light chain antibody, meticulously developed against the reduced and alkylated form of human Thrombospondin 1 (TSP-1), also known as THBS1. Thrombospondin 1 is a pivotal extracellular glycoprotein involved in mediating cell-to-cell and cell-to-matrix interactions, playing essential roles in angiogenesis, wound healing, and immune response regulation. TSP-1 is crucial for platelet aggregation, cell adhesion, migration, and the progression of cells through the growth cycle, thereby significantly influencing tissue development and repair processes. Additionally, TSP-1 modulates the activation of transforming growth factor-beta (TGF-β), a key factor in cellular growth and differentiation, highlighting its importance in maintaining cellular homeostasis. Anti-Thrombospondin 1 antibody (MS-421) demonstrates remarkable species reactivity, effectively recognizing both reduced and non-reduced forms of TSP-1 across mouse, rat, human, equine, bovine, and porcine origins. This broad reactivity makes anti-Thrombospondin 1 antibody (MS-421) an invaluable tool for various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Thrombospondin 1 monoclonal antibody (MS-421) supports advanced research into TSP-1′s roles in cardiovascular diseases, cancer, and inflammatory conditions. Anti-Thrombospondin 1 antibody (MS-421) helps researchers gain deeper insights into the mechanisms and therapeutic potential of TSP-1 in regulating cellular environments and extracellular matrix dynamics, ultimately contributing to the development of targeted treatments and interventions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thrombospondin 1 Antibody (MS-421) | sc-81755 | 200 µg/ml | $316.00 | |||
Thrombospondin 1 Antibody (MS-421): m-IgG Fc BP-HRP Bundle | sc-539662 | 200 µg Ab; 10 µg BP | $354.00 |