Date published: 2025-11-24

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Thrombospondin 1 Activators

Common Thrombospondin 1 Activators include, but are not limited to Bortezomib CAS 179324-69-7, Angiotensin II, Human CAS 4474-91-3, PGE2 CAS 363-24-6, Cholecalciferol CAS 67-97-0 and Retinoic Acid, all trans CAS 302-79-4.

Thrombospondin 1 Activators constitute a distinct class of chemical compounds recognized for their ability to modulate the activity of thrombospondin 1 (TSP-1). This chemical category functions by interacting with and enhancing the signaling pathways associated with TSP-1, an extracellular matrix protein with multifaceted roles in cell-matrix interactions, tissue remodeling, and cellular responses to various cues. TSP-1 is acknowledged for its involvement in diverse biological processes, including cell adhesion, angiogenesis, immune regulation, and wound healing.

Thrombospondin 1 Activators exert their influence through specific molecular interactions that may amplify the downstream effects of TSP-1-mediated signaling, contributing to the fine-tuning of cell-matrix interactions, tissue architecture, and cellular behaviors. The intricate mechanisms through which Thrombospondin 1 Activators impact TSP-1-related pathways remain a focus of ongoing scientific inquiry, providing insights into the intricate crosstalk between cells and their extracellular environment. The specific ways in which this chemical class engages with TSP-1 underscore its significance in unraveling the complexities of cellular communication and enhancing our understanding across various scientific domains.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$132.00
$1064.00
115
(2)

Certain proteasome inhibitors, such as bortezomib, can induce Thrombospondin 1 expression. These inhibitors are used in cancer therapy and can impact the tumor microenvironment.

Heparin

9005-49-6sc-507344
25 mg
$117.00
1
(0)

Heparin is a glycosaminoglycan with anticoagulant properties. It has been shown to induce Thrombospondin 1 expression, affecting cell-matrix interactions and angiogenesis.

Angiotensin II, Human

4474-91-3sc-363643
sc-363643A
sc-363643B
sc-363643C
1 mg
5 mg
25 mg
100 mg
$50.00
$75.00
$260.00
$505.00
3
(1)

Angiotensin II is a hormone that regulates blood pressure and fluid balance. It can stimulate Thrombospondin 1 expression, contributing to vascular remodeling and tissue repair.

PGE2

363-24-6sc-201225
sc-201225C
sc-201225A
sc-201225B
1 mg
5 mg
10 mg
50 mg
$56.00
$156.00
$270.00
$665.00
37
(1)

PGE2 is a lipid signaling molecule with various effects on inflammation and cell behavior. It can induce Thrombospondin 1 expression, impacting tissue repair and angiogenesis.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Vitamin D has immunomodulatory effects and can stimulate Thrombospondin 1 expression, influencing tissue repair and remodeling.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid, a derivative of vitamin A, can induce Thrombospondin 1 expression. It plays a role in tissue development, differentiation, and wound healing.

Atorvastatin

134523-00-5sc-337542A
sc-337542
50 mg
100 mg
$252.00
$495.00
9
(1)

Statins are cholesterol-lowering suggested compounds that have been reported to induce Thrombospondin 1 expression. They have potential implications for vascular health and angiogenesis.