Thrombospondin 1 Activators constitute a distinct class of chemical compounds recognized for their ability to modulate the activity of thrombospondin 1 (TSP-1). This chemical category functions by interacting with and enhancing the signaling pathways associated with TSP-1, an extracellular matrix protein with multifaceted roles in cell-matrix interactions, tissue remodeling, and cellular responses to various cues. TSP-1 is acknowledged for its involvement in diverse biological processes, including cell adhesion, angiogenesis, immune regulation, and wound healing.
Thrombospondin 1 Activators exert their influence through specific molecular interactions that may amplify the downstream effects of TSP-1-mediated signaling, contributing to the fine-tuning of cell-matrix interactions, tissue architecture, and cellular behaviors. The intricate mechanisms through which Thrombospondin 1 Activators impact TSP-1-related pathways remain a focus of ongoing scientific inquiry, providing insights into the intricate crosstalk between cells and their extracellular environment. The specific ways in which this chemical class engages with TSP-1 underscore its significance in unraveling the complexities of cellular communication and enhancing our understanding across various scientific domains.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Certain proteasome inhibitors, such as bortezomib, can induce Thrombospondin 1 expression. These inhibitors are used in cancer therapy and can impact the tumor microenvironment. | ||||||
Heparin | 9005-49-6 | sc-507344 | 25 mg | $117.00 | 1 | |
Heparin is a glycosaminoglycan with anticoagulant properties. It has been shown to induce Thrombospondin 1 expression, affecting cell-matrix interactions and angiogenesis. | ||||||
Angiotensin II, Human | 4474-91-3 | sc-363643 sc-363643A sc-363643B sc-363643C | 1 mg 5 mg 25 mg 100 mg | $50.00 $75.00 $260.00 $505.00 | 3 | |
Angiotensin II is a hormone that regulates blood pressure and fluid balance. It can stimulate Thrombospondin 1 expression, contributing to vascular remodeling and tissue repair. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
PGE2 is a lipid signaling molecule with various effects on inflammation and cell behavior. It can induce Thrombospondin 1 expression, impacting tissue repair and angiogenesis. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D has immunomodulatory effects and can stimulate Thrombospondin 1 expression, influencing tissue repair and remodeling. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a derivative of vitamin A, can induce Thrombospondin 1 expression. It plays a role in tissue development, differentiation, and wound healing. | ||||||
Atorvastatin | 134523-00-5 | sc-337542A sc-337542 | 50 mg 100 mg | $252.00 $495.00 | 9 | |
Statins are cholesterol-lowering suggested compounds that have been reported to induce Thrombospondin 1 expression. They have potential implications for vascular health and angiogenesis. | ||||||