Thrombospondin 1 Antibody (C-9): sc-393503

Thrombospondin 1 Antibody (C-9) is a mouse monoclonal IgG1 kappa light chain antibody designed to target an epitope mapping between amino acids 25-48 near the N-terminus of human Thrombospondin 1 (TSP-1), also known as THBS1. TSP-1 is a key extracellular matrix glycoprotein involved in cell-to-cell and cell-to-matrix communication, playing crucial roles in processes such as angiogenesis, wound healing, and tissue remodeling. Located in the extracellular matrix, TSP-1 interacts with several important proteins, including CD36, CD47, and various integrins, which are essential for mediating cellular adhesion, migration, and proliferation. These interactions are vital for maintaining tissue integrity and facilitating responses to injury and inflammation. Anti-TSP-1 antibody (C-9) exhibits broad species reactivity, effectively recognizing TSP-1 in mouse, rat, and human samples, as well as additional species including equine, bovine, and porcine, making TSP-1 monoclonal antibody (C-9) a versatile tool for applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). By specifically targeting the N-terminal region of TSP-1, anti-TSP-1 antibody (C-9) ensures high specificity and sensitivity, enabling accurate detection and analysis of TSP-1 in various experimental settings. TSP-1 (C-9) antibody is instrumental for researchers studying the intricate interactions and regulatory mechanisms of TSP-1 in cardiovascular diseases, cancer progression, and inflammatory responses. TSP-1 monoclonal antibody (C-9) allows for comprehensive investigation into the molecular pathways mediated by TSP-1, thereby supporting the development of targeted therapeutic strategies aimed at modulating its interactions and functions in diverse biological contexts.

The preferred Thrombospondin 1 antibody is Thrombospondin 1 Antibody (A6.1): sc-59887.