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Thrombospondin 1 Antibody (3F357) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect human Thrombospondin 1 (TSP-1), also known as THBS1, a crucial glycoprotein involved in cell-to-cell and cell-to-matrix communication. Anti-Thrombospondin 1 antibody (3F357) targets an epitope on reduced and alkylated TSP-1, ensuring robust performance in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP) applications. TSP-1 plays a vital role in regulating angiogenesis, platelet aggregation, tissue repair, and cellular adhesion and migration by interacting with key proteins such as CD36, CD47, various integrins, vascular endothelial growth factor (VEGF), and matrix metalloproteinases (MMPs). Thrombospondin 1 monoclonal antibody (3F357) exhibits broad species reactivity, effectively recognizing both reduced and non-reduced forms of TSP-1 across mouse, rat, human, equine, bovine, porcine, and canine samples. Anti-Thrombospondin 1 antibody (3F357) enables detailed studies of TSP-1 interactions and functions in diverse biological processes, including extracellular matrix dynamics and cell growth cycle progression. TSP-1 is stored in platelet α-granules and is released upon activation, contributing to platelet aggregation and adhesion during hemostasis. Thrombospondin 1 (3F357) antibody is an essential tool for researchers exploring the molecular mechanisms of development, wound healing, and various disease pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thrombospondin 1 Antibody (3F357) | sc-73158 | 200 µg/ml | $316.00 | |||
Thrombospondin 1 Antibody (3F357) Alexa Fluor® 647 | sc-73158 AF647 | 200 µg/ml | $357.00 |