Date published: 2025-12-14

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Thrombospondin 1 Antibody (3F357): sc-73158

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Datasheets
  • Thrombospondin 1 Antibody (3F357) is a mouse monoclonal IgG1 κ, cited in 12 publications, provided at 200 µg/ml
  • raised against reduced and alkylated Thrombospondin 1 of human origin
  • recommended for detection of reduced and non-reduced Thrombospondin 1 of mouse, rat, human, equine, bovine, porcine and canine origin by WB, IP, IF and IHC(P)
  • also available conjugated to Alexa Fluor® 647, for IF, IHC(P) and FCM
  • See Thrombospondin 1 (C-8): sc-393504 for Thrombospondin 1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Thrombospondin 1 Antibody (3F357). This work is in progress.

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Thrombospondin 1 Antibody (3F357) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect human Thrombospondin 1 (TSP-1), also known as THBS1, a crucial glycoprotein involved in cell-to-cell and cell-to-matrix communication. Anti-Thrombospondin 1 antibody (3F357) targets an epitope on reduced and alkylated TSP-1, ensuring robust performance in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP) applications. TSP-1 plays a vital role in regulating angiogenesis, platelet aggregation, tissue repair, and cellular adhesion and migration by interacting with key proteins such as CD36, CD47, various integrins, vascular endothelial growth factor (VEGF), and matrix metalloproteinases (MMPs). Thrombospondin 1 monoclonal antibody (3F357) exhibits broad species reactivity, effectively recognizing both reduced and non-reduced forms of TSP-1 across mouse, rat, human, equine, bovine, porcine, and canine samples. Anti-Thrombospondin 1 antibody (3F357) enables detailed studies of TSP-1 interactions and functions in diverse biological processes, including extracellular matrix dynamics and cell growth cycle progression. TSP-1 is stored in platelet α-granules and is released upon activation, contributing to platelet aggregation and adhesion during hemostasis. Thrombospondin 1 (3F357) antibody is an essential tool for researchers exploring the molecular mechanisms of development, wound healing, and various disease pathologies.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Thrombospondin 1 Antibody (3F357)

sc-73158
200 µg/ml
$316.00

Thrombospondin 1 Antibody (3F357) Alexa Fluor® 647

sc-73158 AF647
200 µg/ml
$357.00

Are there any issues with using sc-73158: Thrombospondin 1 (3F357) mouse monoclonal primary antibody on mouse samples?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-73158 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 4 out of 5 by from Single strong band in CCDSingle strong band in CCD-1064Sk whole cell lysate. -SCBT QC
Date published: 2015-03-29
Rated 4 out of 5 by from Published IHC and WB data with mouse 4T1Published IHC and WB data with mouse 4T1 and breast cancer cell line - SCBT Publication Review
Date published: 2014-01-04
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Thrombospondin 1 Antibody (3F357) is rated 4.0 out of 5 by 2.
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