TET2 Antibody (C-7): sc-398535
- TET2 Antibody (C-7) is a mouse monoclonal IgG2b κ TET2 antibody, cited in 9 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of TET2 of human origin
- TET2 Antibody (C-7) is recommended for detection of TET2 of and human origin by WB, IP, IF and ELISA
- Anti-TET2 Antibody (C-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for TET2 Antibody (C-7) for WB applications. These reagents are now offered in bundles with TET2 Antibody (C-7) (see ordering information below).
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TET2 Antibody (C-7) is a mouse monoclonal IgG2b kappa light chain antibody designed to detect TET2 in various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TET2 monoclonal antibody (C-7) targets the N-terminal region of human TET2, specifically amino acids 1-300, ensuring robust and reliable binding. TET2 is a critical enzyme involved in DNA demethylation, playing a vital role in epigenetic regulation and maintenance of normal hematopoiesis. Proper functioning of TET2 is essential for preventing aberrant cell growth, and mutations are frequently associated with myeloid malignancies and other cancers, highlighting importance in both normal physiology and disease. TET2 (C-7) antibody is available in various conjugated forms, including horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, as well as an agarose-conjugated version, providing flexibility for diverse experimental needs. Expressed in multiple tissues such as brain, kidney, heart, lung, muscle, and stomach, TET2 exists in three alternatively spliced isoforms, each contributing to diverse biological functions. Anti-TET2 antibody (C-7) enables researchers to investigate TET2′s role in gene regulation, development, and disease mechanisms with high precision and specificity. Additionally, TET2 (C-7) antibody has been validated for use in both human and murine models, making this reagent a versatile tool for comparative studies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TET2 Antibody (C-7) References:
- Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. | Nagase, T., et al. 2000. DNA Res. 7: 273-81. PMID: 10997877
- Frequent deletion of chromosome 3 in malignant sporadic pancreatic endocrine tumors. | Guo, SS., et al. 2002. Mol Cell Endocrinol. 190: 109-14. PMID: 11997184
- TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). | Lorsbach, RB., et al. 2003. Leukemia. 17: 637-41. PMID: 12646957
- Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. | Okazaki, N., et al. 2003. DNA Res. 10: 167-80. PMID: 14621295
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. | Hillier, LW., et al. 2005. Nature. 434: 724-31. PMID: 15815621
- [Generation of Ayu17-449 gene knockout mice by gene trapping]. | Tang, H., et al. 2006. Yi Chuan. 28: 129-32. PMID: 16520305
- Cloning and expression analysis of a murine novel gene, Ayu17-449. | Tang, H., et al. 2006. Yi Chuan Xue Bao. 33: 413-9. PMID: 16722336
- Characterization of Ayu17-449 gene expression and resultant kidney pathology in a knockout mouse model. | Tang, H., et al. 2008. Transgenic Res. 17: 599-608. PMID: 18288583
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TET2 Antibody (C-7) | sc-398535 | 200 µg/ml | $322.00 | |||
TET2 Antibody (C-7): m-IgG Fc BP-HRP Bundle | sc-526315 | 200 µg Ab; 10 µg BP | $361.00 | |||
TET2 Antibody (C-7): m-IgG2b BP-HRP Bundle | sc-549712 | 200 µg Ab; 10 µg BP | $361.00 | |||
TET2 Antibody (C-7) AC | sc-398535 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TET2 Antibody (C-7) HRP | sc-398535 HRP | 200 µg/ml | $322.00 | |||
TET2 Antibody (C-7) FITC | sc-398535 FITC | 200 µg/ml | $336.00 | |||
TET2 Antibody (C-7) PE | sc-398535 PE | 200 µg/ml | $349.00 | |||
TET2 Antibody (C-7) Alexa Fluor® 488 | sc-398535 AF488 | 200 µg/ml | $364.00 | |||
TET2 Antibody (C-7) Alexa Fluor® 546 | sc-398535 AF546 | 200 µg/ml | $364.00 | |||
TET2 Antibody (C-7) Alexa Fluor® 594 | sc-398535 AF594 | 200 µg/ml | $364.00 | |||
TET2 Antibody (C-7) Alexa Fluor® 647 | sc-398535 AF647 | 200 µg/ml | $364.00 | |||
TET2 Antibody (C-7) Alexa Fluor® 680 | sc-398535 AF680 | 200 µg/ml | $364.00 | |||
TET2 Antibody (C-7) Alexa Fluor® 790 | sc-398535 AF790 | 200 µg/ml | $364.00 |