Streptolysin S biosynthesis protein Antibody (G-11): sc-398634

Streptolysin S biosynthesis protein Antibody (G-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects Streptolysin S biosynthesis protein of Streptococcus equi origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Streptolysin S biosynthesis protein antibody (G-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Streptolysin S biosynthesis protein (G-11) antibody plays a crucial role in studying the pathogenicity of Streptococcus equi, as Streptolysin S biosynthesis protein is involved in producing streptolysin S, a potent cytolysin that contributes to bacterial evasion of host immune response and disease progression. Streptolysin S biosynthesis protein functions are vital for bacterial virulence, including lysing red blood cells and immune cells, leading to tissue damage and infection spread. Understanding streptolysin S production mechanisms and host tissue effects helps develop targeted therapies and vaccines against strangles, a highly contagious disease causing severe respiratory symptoms and lymphadenitis in horses. Infection primarily spreads through inhalation or direct contact with infected animals, making Streptolysin S biosynthesis protein research critical for controlling outbreaks and improving equine health.

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Streptolysin S biosynthesis protein Antibody (G-11) References:

1. Getting to grips with strangles: an effective multi-component recombinant vaccine for the protection of horses from Streptococcus equi infection.  |  Guss, B., et al. 2009. PLoS Pathog. 5: e1000584. PMID: 19763180
2. Molecular characterisation of 'strangles' outbreaks in the UK: the use of M-protein typing of Streptococcus equi ssp. equi.  |  Ivens, PA., et al. 2011. Equine Vet J. 43: 359-64. PMID: 21492215
3. Association of Streptococcus equi with equine monocytes.  |  Mérant, C., et al. 2011. Vet Immunol Immunopathol. 143: 83-6. PMID: 21752476
4. Streptococcus equi: a pathogen restricted to one host.  |  Waller, AS., et al. 2011. J Med Microbiol. 60: 1231-1240. PMID: 21757503
5. Streptococcus equi subspecies equi infection (strangles) in horses.  |  Boyle, A. 2011. Compend Contin Educ Vet. 33: E1-7; quiz E8. PMID: 21870348
6. Antiphagocytic function of an IgG glycosyl hydrolase from Streptococcus equi subsp. equi and its use as a vaccine component.  |  Flock, M., et al. 2012. Infect Immun. 80: 2914-9. PMID: 22615244
7. Development of a novel mucosal vaccine against strangles by supercritical enhanced atomization spray-drying of Streptococcus equi extracts and evaluation in a mouse model.  |  Rodrigues, MA., et al. 2012. Eur J Pharm Biopharm. 82: 392-400. PMID: 22841882
8. Detection of Streptococcus equi subspecies equi using a triplex qPCR assay.  |  Webb, K., et al. 2013. Vet J. 195: 300-4. PMID: 22884566

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Streptolysin S biosynthesis protein Antibody (G-11) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Streptolysin S biosynthesis protein Antibody (G-11) Specifications

Alternate Product Name: Streptolysin S biosynthesis protein

Product Clone Name: G-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 1-354

Epitope Target: Streptolysin S biosynthesis protein

Epitope Species: Streptococcus equi subsp. equi 4047

Product Reactivity/Detection: Streptolysin S biosynthesis protein

Species Reactivity/Detection: Streptococcus equi

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Streptolysin S biosynthesis protein Antibody (G-11): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin