Stat5a Antibody (C-10): sc-166465
- Stat5a Antibody (C-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 774-793 at the C-terminus of Stat5a of mouse origin
- recommended for detection of Stat5a of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-166465 X, 200 µg/0.1 ml)
- See Stat5a (C-6): sc-271542 for Stat5a antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Stat5a Antibody (C-10) for WB applications. These reagents are now offered in bundles with Stat5a Antibody (C-10) (see ordering information below).
Stat5a Antibody (C-10) is a mouse monoclonal IgG1 kappa light chain antibody, specifically targeting an epitope within amino acids 774-793 at the C-terminus of the Signal Transducer and Activator of Transcription 5A (Stat5a) protein, also known as STAT5A. Anti-Stat5a antibody (C-10) recognizes Stat5a across multiple species, including mouse, rat, and human, and is recommended for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA) applications. Stat5a, along with its closely related isoform Stat5b, plays a critical role in cellular signaling pathways initiated by cytokines and growth factors such as IL-2, IL-3, and erythropoietin. Structurally, Stat5a contains distinct domains essential for its function, including the SH2 domain which facilitates dimerization upon phosphorylation, enabling translocation to the nucleus where Stat5a regulates gene transcription. The C-terminal region targeted by Stat5a (C-10) monoclonal antibody is vital for Stat5a′s stability and interaction with DNA, underscoring the importance of recognizing this specific epitope. Proper structural configuration of Stat5a is crucial for promoting proliferation, differentiation, and apoptosis in lymphohematopoietic cells, as well as in maintaining normal immune function. Aberrations in Stat5a signaling have been implicated in various malignancies and immune disorders, making anti-Stat5a antibody (C-10) a valuable tool for research and diagnostic purposes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Stat5a Antibody (C-10) | sc-166465 | 200 µg/ml | $322.00 | |||
Stat5a Antibody (C-10): m-IgGκ BP-HRP Bundle | sc-534774 | 200 µg Ab; 40 µg BP | $361.00 | |||
Stat5a Antibody (C-10): m-IgG1 BP-HRP Bundle | sc-538874 | 200 µg Ab; 20 µg BP | $361.00 | |||
Stat5a (C-10) Neutralizing Peptide | sc-166465 P | 100 µg/0.5 ml | $69.00 | |||
Stat5a Antibody (C-10) X | sc-166465 X | 200 µg/0.1 ml | $322.00 |