SSH3 Antibody (B-7): sc-390058
- SSH3 Antibody (B-7) is a mouse monoclonal IgG1 κ SSH3 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 431-649 mapping at the C-terminus of SSH3 of mouse origin
- SSH3 Antibody (B-7) is recommended for detection of SSH3 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-SSH3 Antibody (B-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SSH3 Antibody (B-7) for WB applications. These reagents are now offered in bundles with SSH3 Antibody (B-7) (see ordering information below).
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SSH3 Antibody (B-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects SSH3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SSH3 (B-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SSH3, also known as Slingshot homolog 3 or SSH3L, is a 659 amino acid protein localized in both nucleus and cytoplasm, serving as a human homolog of the Drosophila slingshot (ssh) protein. SSH3 functions as a protein phosphatase, playing a crucial role in regulating actin filament dynamics through interaction with actin-depolymerizing factor (ADF) and Cofilin, which are key players in rapid depolymerization and disassembly of F-actin. The ADF/Cofilin family responds to various stimuli and can be inactivated by different kinases, making SSH3′s role in dephosphorylating these proteins vital for their reactivation and subsequent regulation of actin dynamics. SSH3 contains one tyrosine-protein phosphatase domain and is expressed as five isoforms due to alternative splicing, highlighting SSH3′s complexity and potential for diverse regulatory functions in cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SSH3 Antibody (B-7) | sc-390058 | 200 µg/ml | $316.00 | |||
SSH3 Antibody (B-7): m-IgGκ BP-HRP Bundle | sc-523390 | 200 µg Ab, 40 µg BP | $354.00 | |||
SSH3 Antibody (B-7): m-IgG1 BP-HRP Bundle | sc-533576 | 200 µg Ab; 20 µg BP | $354.00 | |||
SSH3 Antibody (B-7) AC | sc-390058 AC | 500 µg/ml, 25% agarose | $416.00 | |||
SSH3 Antibody (B-7) HRP | sc-390058 HRP | 200 µg/ml | $316.00 | |||
SSH3 Antibody (B-7) FITC | sc-390058 FITC | 200 µg/ml | $330.00 | |||
SSH3 Antibody (B-7) PE | sc-390058 PE | 200 µg/ml | $343.00 | |||
SSH3 Antibody (B-7) Alexa Fluor® 488 | sc-390058 AF488 | 200 µg/ml | $357.00 | |||
SSH3 Antibody (B-7) Alexa Fluor® 546 | sc-390058 AF546 | 200 µg/ml | $357.00 | |||
SSH3 Antibody (B-7) Alexa Fluor® 594 | sc-390058 AF594 | 200 µg/ml | $357.00 | |||
SSH3 Antibody (B-7) Alexa Fluor® 647 | sc-390058 AF647 | 200 µg/ml | $357.00 | |||
SSH3 Antibody (B-7) Alexa Fluor® 680 | sc-390058 AF680 | 200 µg/ml | $357.00 | |||
SSH3 Antibody (B-7) Alexa Fluor® 790 | sc-390058 AF790 | 200 µg/ml | $357.00 |