Squalene synthetase Antibody (C-10): sc-271143
- Squalene synthetase Antibody (C-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of Squalene synthetase of human origin
- recommended for detection of Squalene synthetase of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Squalene synthetase Antibody (C-10) for WB and IHC(P) applications. These reagents are now offered in bundles with Squalene synthetase Antibody (C-10) (see ordering information below).
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Squalene synthetase Antibody (C-10) is a mouse monoclonal IgG1 antibody that detects Squalene synthetase in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Squalene synthetase plays a crucial role in cholesterol biosynthesis by catalyzing the conversion of transfarnesyl-diphosphate to squalene, marking the first specific step in the cholesterol biosynthetic pathway. This enzyme is strategically located at a branch point in the mevalonate pathway, which is essential for the production of isoprenoids, a class of compounds that are vital for various cellular functions, including membrane integrity and signaling. The importance of Squalene synthetase extends beyond enzymatic activity; anti-Squalene synthetase antibody (C-10) has revealed involvement in the regulation of cholesterol levels within cells, which is critical for maintaining cellular homeostasis and preventing diseases related to cholesterol dysregulation. Additionally, Squalene synthetase may interact with Squalene epoxidase, another key enzyme in sterol biosynthesis, potentially forming a complex that influences the overall efficiency of cholesterol production. Squalene synthetase (C-10) antibody serves as an invaluable tool for researchers studying lipid metabolism and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Squalene synthetase Antibody (C-10) | sc-271143 | 200 µg/ml | $316.00 | |||
Squalene synthetase Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-540211 | 200 µg Ab; 10 µg BP | $354.00 | |||
Squalene synthetase Antibody (C-10): m-IgG1 BP-HRP Bundle | sc-541974 | 200 µg Ab; 20 µg BP | $354.00 |