spectrin β I Antibody (B-2): sc-377437

spectrin β I Antibody (B-2) is a mouse monoclonal IgG3 antibody that detects spectrin β I in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). spectrin β I plays a crucial role in maintaining the structural integrity and stability of the cytoskeleton, particularly in erythrocytes, where spectrin β I forms a vital component of the membrane cytoskeleton. spectrin β I interacts with spectrin α I to form heterodimers, which then assemble into larger spectrin tetramers that provide mechanical support and flexibility to the plasma membrane. Proper functioning of spectrin β I is essential for maintaining the biconcave shape of red blood cells, allowing them to deform as they navigate through narrow capillaries, which is critical for efficient oxygen transport throughout the body. Additionally, spectrin β I is involved in various cellular processes, including cell signaling and the organization of membrane proteins, highlighting spectrin β I′s importance beyond structural support. anti-spectrin β I antibody (B-2) effectively targets spectrin β I, making anti-spectrin β I antibody (B-2) an invaluable tool for researchers studying cytoskeletal dynamics and related cellular functions.

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spectrin β I Antibody (B-2) References:

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6. New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approach.  |  Zufferey, A., et al. 2016. Hum Genet. 135: 403-414. PMID: 26883867
7. Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method.  |  Hu, Y., et al. 2018. J Clin Endocrinol Metab. 103: 125-138. PMID: 29145611
8. Gene's co-expression network and experimental validation of molecular markers associated with the drug resistance of gastric cancer.  |  Qi, W. and Zhang, Q. 2020. Biomark Med. 14: 761-773. PMID: 32715733
9. Impaired reciprocal regulation between SIRT6 and TGF-β signaling in fatty liver.  |  Xiang, X., et al. 2022. FASEB J. 36: e22335. PMID: 35506565
10. Gene Expression Characteristics of Tumor and Adjacent Non-Tumor Tissues of Pancreatic Ductal Adenocarcinoma (PDAC) In-Silico.  |  Güven, E. 2022. Iran J Biotechnol. 20: e3092. PMID: 35891953

The preferred spectrin β I antibody is spectrin β I Antibody (B-1): sc-374309.