SPATA10 Antibody (C-11): sc-390306
- SPATA10 Antibody (C-11) is a mouse monoclonal IgG1 κ SPATA10 antibody, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 135-175 within an internal region of SPATA10 of human origin
- SPATA10 Antibody (C-11) is recommended for detection of SPATA10 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-SPATA10 Antibody (C-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SPATA10 Antibody (C-11) for WB and IHC(P) applications. These reagents are now offered in bundles with SPATA10 Antibody (C-11) (see ordering information below).
SPATA10 Antibody (C-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects SPATA10 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). SPATA10 (C-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SPATA10 protein, also known as SPATS2 (spermatogenesis-associated serine-rich protein 2), SCR59 (serine-rich spermatocytes and round spermatid 59 kDa protein), or p59scr, is a 545 amino acid cytoplasmic protein that plays a crucial role in spermatogenesis, particularly in sperm cell development and maturation. SPATA10 function is essential for male fertility, as disruptions in SPATA10 expression can lead to impaired spermatogenesis and associated infertility issues. SPATA10 gene is located on human chromosome 12q13.12 and mouse chromosome 15 F1, a region linked to various skeletal deformities and developmental disorders. Understanding SPATA10′s role in cellular processes not only sheds light on male reproductive health but also provides insights into potential therapeutic targets for treating infertility.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SPATA10 Antibody (C-11) References:
- [Achondrogenesis type II-hypochondrogenesis: radiological features.Case report]. | Delgado Carrasco, J., et al. 2001. An Esp Pediatr. 55: 553-7. PMID: 11730591
- Identification of a novel protein p59(scr), which is expressed at specific stages of mouse spermatogenesis. | Senoo, M., et al. 2002. Biochem Biophys Res Commun. 292: 992-8. PMID: 11944913
- Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma. | Ohira, M., et al. 2003. Cancer Lett. 197: 63-8. PMID: 12880961
- A case of Kniest dysplasia with retinal detachment and the mutation analysis. | Yokoyama, T., et al. 2003. Am J Ophthalmol. 136: 1186-8. PMID: 14644246
- A familial case of achondrogenesis type II caused by a dominant COL2A1 mutation and 'patchy' expression in the mosaic father. | Forzano, F., et al. 2007. Am J Med Genet A. 143A: 2815-20. PMID: 17994563
- Visceral manifestations of hypochondrogenesis. | Wainwright, H. and Beighton, P. 2008. Virchows Arch. 453: 203-7. PMID: 18642028
- Trisomy 12p and monosomy 4p: phenotype-genotype correlation. | Benussi, DG., et al. 2009. Genet Test Mol Biomarkers. 13: 199-204. PMID: 19378504
- High resolution melting analysis for mutation detection for PTPN11 gene: applications of this method for diagnosis of Noonan syndrome. | Lo, FS., et al. 2009. Clin Chim Acta. 409: 75-7. PMID: 19737548
- Cytogenetic and molecular analysis in trisomy 12p. | Allen, TL., et al. 1996. Am J Med Genet. 63: 250-6. PMID: 8723118
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SPATA10 Antibody (C-11) | sc-390306 | 200 µg/ml | $322.00 | |||
SPATA10 Antibody (C-11): m-IgGκ BP-HRP Bundle | sc-523484 | 200 µg Ab, 40 µg BP | $361.00 | |||
SPATA10 Antibody (C-11): m-IgG1 BP-HRP Bundle | sc-533587 | 200 µg Ab; 20 µg BP | $361.00 | |||
SPATA10 Antibody (C-11) AC | sc-390306 AC | 500 µg/ml, 25% agarose | $424.00 | |||
SPATA10 Antibody (C-11) HRP | sc-390306 HRP | 200 µg/ml | $322.00 | |||
SPATA10 Antibody (C-11) FITC | sc-390306 FITC | 200 µg/ml | $336.00 | |||
SPATA10 Antibody (C-11) PE | sc-390306 PE | 200 µg/ml | $349.00 | |||
SPATA10 Antibody (C-11) Alexa Fluor® 488 | sc-390306 AF488 | 200 µg/ml | $364.00 | |||
SPATA10 Antibody (C-11) Alexa Fluor® 546 | sc-390306 AF546 | 200 µg/ml | $364.00 | |||
SPATA10 Antibody (C-11) Alexa Fluor® 594 | sc-390306 AF594 | 200 µg/ml | $364.00 | |||
SPATA10 Antibody (C-11) Alexa Fluor® 647 | sc-390306 AF647 | 200 µg/ml | $364.00 | |||
SPATA10 Antibody (C-11) Alexa Fluor® 680 | sc-390306 AF680 | 200 µg/ml | $364.00 | |||
SPATA10 Antibody (C-11) Alexa Fluor® 790 | sc-390306 AF790 | 200 µg/ml | $364.00 | |||
SPATA10 (C-11) Neutralizing Peptide | sc-390306 P | 100 µg/0.5 ml | $69.00 |