SPATA10, or Spermatogenesis Associated Protein 10, plays a crucial role in the process of spermatogenesis, which is the development and maturation of sperm cells within the testes. This protein is thought to be essential for the proper formation of spermatozoa, particularly influencing key aspects such as sperm cell differentiation, motility, and the structural integrity of sperm. The exact functional mechanisms of SPATA10 in these processes remain not fully elucidated, but its association with spermatogenesis indicates a significant role in the orchestration of molecular interactions and signaling pathways that ensure the production of viable sperm cells. Given its importance in reproductive biology, SPATA10's activity is likely finely tuned by a series of regulatory mechanisms that ensure its function is executed at the correct developmental stages and under appropriate physiological conditions.
The activation of SPATA10 is thought to be regulated through several pathways that ensure its timely and precise function in sperm development. One primary mechanism likely involves transcriptional activation, where specific transcription factors induce the expression of the SPATA10 gene during key stages of sperm cell maturation. This transcriptional regulation ensures that SPATA10 protein is synthesized when it is needed for critical developmental transitions. Additionally, the localization of SPATA10 within sperm cells may be controlled by signaling molecules that guide it to specific cellular compartments where its function is required. For instance, during the stages of sperm motility development, SPATA10 might be directed to the developing flagella or other motility-associated structures.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Dibutyryl-cAMP is an analog of cAMP and can activate protein kinase A (PKA). PKA signaling is essential for spermatogenesis. The activation of PKA can potentially enhance the expression or function of SPATA10, given its role in spermatogenesis. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels. Given that cAMP is crucial in spermatogenesis, the elevation of cAMP levels can enhance the processes where SPATA10 plays a role. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
An inhibitor of phosphodiesterase 4, which results in increased cAMP levels. Elevated cAMP can, in turn, influence processes like spermatogenesis and potentially enhance SPATA10 function. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A derivative of vitamin A, retinoic acid is essential for spermatogonia differentiation. By promoting this differentiation, it can indirectly influence the function or expression of SPATA10. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Although commonly associated with female reproduction, estradiol can also influence spermatogenesis. By modulating spermatogenic processes, estradiol can indirectly impact SPATA10. | ||||||
DHEA | 53-43-0 | sc-202573 | 10 g | $111.00 | 3 | |
A precursor to both testosterone and estradiol, DHEA can influence spermatogenesis. The induced hormonal changes can indirectly impact the function or expression of SPATA10. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $57.00 $607.00 $176.00 | ||
Involved in cellular growth and proliferation, spermidine can promote spermatogenic processes. Given its role, it can influence the function or expression of SPATA10. | ||||||
Spermine | 71-44-3 | sc-212953A sc-212953 sc-212953B sc-212953C | 1 g 5 g 25 g 100 g | $61.00 $196.00 $277.00 $901.00 | 1 | |
Similar to spermidine, spermine is involved in cellular growth. Its influence on spermatogenesis can, in turn, affect the function or expression of SPATA10. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Known to protect DNA from oxidative stress, which is crucial for spermatogenesis. By preserving the integrity of spermatogenic processes, it can potentially enhance the function or expression of SPATA10. | ||||||