Date published: 2026-4-24

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SPACR Antibody (A-2): sc-376793

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Datasheets
  • SPACR Antibody (A-2) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against amino acids 121-420 mapping within an internal region of SPACR of human origin
  • recommended for detection of SPACR of human origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for SPACR Antibody (A-2) for WB applications. These reagents are now offered in bundles with SPACR Antibody (A-2) (see ordering information below).
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    SPACR Antibody (A-2) is a mouse monoclonal IgG1 antibody that detects SPACR in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SPACR, also known as interphotoreceptor matrix proteoglycan 1 (IMPG1) or IPM150, is a 797 amino acid secreted protein characterized by two SEA domains, which are crucial for retinal function. SPACR plays a vital role in forming the interphotoreceptor matrix, a specialized extracellular matrix that supports the structural integrity and function of photoreceptor cells, including cones and rods. SPACR′s interaction with hyaluronan contributes to forming a macromolecular scaffold that maintains retinal architecture organization, facilitating proper visual signal transduction. SPACR is predominantly expressed in the retina, where SPACR is essential for photoreceptor cell health and functionality, and SPACR′s gene is located on human chromosome 6q14, a region associated with various genetic disorders. Anti-SPACR antibody (A-2) serves as an invaluable tool for researchers studying retinal biology and related diseases, providing insights into molecular mechanisms underlying vision and potential therapeutic targets for retinal disorders.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    SPACR Antibody (A-2)

    sc-376793
    200 µg/ml
    $322.00

    SPACR Antibody (A-2): m-IgG Fc BP-HRP Bundle

    sc-540647
    200 µg Ab; 10 µg BP
    $361.00

    SPACR Antibody (A-2): m-IgG1 BP-HRP Bundle

    sc-542266
    200 µg Ab; 20 µg BP
    $361.00

    How much sample do you recommend loading on the gel for Western blot detection using SPACR (A-2): sc-376793?

    Asked by: Germaine
    We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Good Western Blot data of SPACR expression in nonGood Western Blot data of SPACR expression in non-transfected and human SPACR transfected 293T whole cell lysates. -SCBT QC
    Date published: 2015-04-13
    Rated 5 out of 5 by from Produced positive Western Blot data of SPACRProduced positive Western Blot data of SPACR expression in human eye tissue extract and Y79 and ARPE-19 whole cell lysates. -SCBT QC
    Date published: 2014-02-04
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    SPACR Antibody (A-2) is rated 5.0 out of 5 by 2.
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