


SPACR Antibody (A-2) is a mouse monoclonal IgG1 antibody that detects SPACR in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SPACR, also known as interphotoreceptor matrix proteoglycan 1 (IMPG1) or IPM150, is a 797 amino acid secreted protein characterized by two SEA domains, which are crucial for retinal function. SPACR plays a vital role in forming the interphotoreceptor matrix, a specialized extracellular matrix that supports the structural integrity and function of photoreceptor cells, including cones and rods. SPACR′s interaction with hyaluronan contributes to forming a macromolecular scaffold that maintains retinal architecture organization, facilitating proper visual signal transduction. SPACR is predominantly expressed in the retina, where SPACR is essential for photoreceptor cell health and functionality, and SPACR′s gene is located on human chromosome 6q14, a region associated with various genetic disorders. Anti-SPACR antibody (A-2) serves as an invaluable tool for researchers studying retinal biology and related diseases, providing insights into molecular mechanisms underlying vision and potential therapeutic targets for retinal disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SPACR Antibody (A-2) | sc-376793 | 200 µg/ml | $322.00 | |||
SPACR Antibody (A-2): m-IgG Fc BP-HRP Bundle | sc-540647 | 200 µg Ab; 10 µg BP | $361.00 | |||
SPACR Antibody (A-2): m-IgG1 BP-HRP Bundle | sc-542266 | 200 µg Ab; 20 µg BP | $361.00 |