SNAT5 Antibody (G-7): sc-515813
- SNAT5 Antibody (G-7) is a mouse monoclonal IgG1 κ SNAT5 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 218-266 mapping within an internal region of SNAT5 of human origin
- SNAT5 Antibody (G-7) is recommended for detection of SNAT5 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-SNAT5 Antibody (G-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SNAT5 Antibody (G-7) for WB applications. These reagents are now offered in bundles with SNAT5 Antibody (G-7) (see ordering information below).
QUICK LINKS
SNAT5 Antibody (G-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects SNAT5 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SNAT5 (G-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SNAT5 protein, also known as SLC38A5, plays a crucial role in the transport of neutral amino acids across cell membranes, which is vital for numerous physiological processes, including neurotransmitter cycling and metabolic regulation. SNAT5 is particularly important in the central nervous system, where SNAT5 participates in the glutamate-glutamine cycle, facilitating the efflux of glutamine from glial cells, thus maintaining the balance of neurotransmitters essential for proper brain function. SNAT5 is expressed in various mammalian tissues, with a notable distribution in the neocortex, hippocampus, striatum, and spinal cord, highlighting SNAT5′s significance in both neural activity and overall metabolic homeostasis. SNAT5′s ability to interact with other proteins involved in amino acid transport further underscores SNAT5′s importance in cellular nutrient uptake and signaling pathways, making anti-SNAT5 antibody (G-7) an invaluable tool for researchers studying amino acid transport mechanisms and their implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SNAT5 Antibody (G-7) References:
- Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family. | Mackenzie, B. and Erickson, JD. 2004. Pflugers Arch. 447: 784-95. PMID: 12845534
- Increased expression of a glutamine transporter SNAT3 is a marker of malignant gliomas. | Sidoryk, M., et al. 2004. Neuroreport. 15: 575-8. PMID: 15094455
- Bidirectional substrate fluxes through the system N (SNAT5) glutamine transporter may determine net glutamine flux in rat liver. | Baird, FE., et al. 2004. J Physiol. 559: 367-81. PMID: 15218073
- Amino acid transporter SNAT5 localizes to glial cells in the rat brain. | Cubelos, B., et al. 2005. Glia. 49: 230-44. PMID: 15390093
- Type I diabetes affects skeletal muscle glutamine uptake in a fiber-specific manner. | Onan, MC., et al. 2005. Exp Biol Med (Maywood). 230: 606-11. PMID: 16179728
- Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cells. | Umapathy, NS., et al. 2005. Invest Ophthalmol Vis Sci. 46: 3980-7. PMID: 16249471
- Evidence for allosteric regulation of pH-sensitive System A (SNAT2) and System N (SNAT5) amino acid transporter activity involving a conserved histidine residue. | Baird, FE., et al. 2006. Biochem J. 397: 369-75. PMID: 16629640
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SNAT5 Antibody (G-7) | sc-515813 | 200 µg/ml | $316.00 | |||
SNAT5 Antibody (G-7): m-IgG Fc BP-HRP Bundle | sc-531521 | 200 µg Ab; 10 µg BP | $354.00 | |||
SNAT5 Antibody (G-7): m-IgGκ BP-HRP Bundle | sc-525232 | 200 µg Ab, 40 µg BP | $354.00 | |||
SNAT5 Antibody (G-7): m-IgG1 BP-HRP Bundle | sc-544605 | 200 µg Ab; 20 µg BP | $354.00 | |||
SNAT5 Antibody (G-7) AC | sc-515813 AC | 500 µg/ml, 25% agarose | $416.00 | |||
SNAT5 Antibody (G-7) HRP | sc-515813 HRP | 200 µg/ml | $316.00 | |||
SNAT5 Antibody (G-7) FITC | sc-515813 FITC | 200 µg/ml | $330.00 | |||
SNAT5 Antibody (G-7) PE | sc-515813 PE | 200 µg/ml | $343.00 | |||
SNAT5 Antibody (G-7) Alexa Fluor® 488 | sc-515813 AF488 | 200 µg/ml | $357.00 | |||
SNAT5 Antibody (G-7) Alexa Fluor® 546 | sc-515813 AF546 | 200 µg/ml | $357.00 | |||
SNAT5 Antibody (G-7) Alexa Fluor® 594 | sc-515813 AF594 | 200 µg/ml | $357.00 | |||
SNAT5 Antibody (G-7) Alexa Fluor® 647 | sc-515813 AF647 | 200 µg/ml | $357.00 | |||
SNAT5 Antibody (G-7) Alexa Fluor® 680 | sc-515813 AF680 | 200 µg/ml | $357.00 | |||
SNAT5 Antibody (G-7) Alexa Fluor® 790 | sc-515813 AF790 | 200 µg/ml | $357.00 |