SMUG1 Antibody (D-2): sc-377370
- SMUG1 Antibody (D-2) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 39-75 near the N-terminus of SMUG1 of human origin
- recommended for detection of SMUG1 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SMUG1 Antibody (D-2). This work is in progress.
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SEE ALSO...
SMUG1 Antibody (D-2) is a mouse monoclonal IgG1 antibody that detects SMUG1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SMUG1, or single-strand selective monofunctional uracil DNA glycosylase, plays a crucial role in the base excision repair (BER) pathway by specifically recognizing and excising uracil from DNA, thereby preventing the incorporation of incorrect bases that can lead to mutations and genomic instability. SMUG1 is predominantly located in the nucleus, where SMUG1 interacts with chromatin to maintain DNA integrity, highlighting its importance in cellular processes such as DNA replication and repair. The human SMUG1 gene is mapped to chromosome 12q13.13, and SMUG1 expression is vital for cellular health, as deficiencies in SMUG1 can result in increased susceptibility to DNA damage and contribute to various diseases, including cancer. anti-SMUG1 antibody (D-2) is an essential tool for researchers studying DNA repair mechanisms and the implications of uracil misincorporation in genomic stability.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SMUG1 Antibody (D-2) | sc-377370 | 200 µg/ml | $322.00 | |||
SMUG1 (D-2) Neutralizing Peptide | sc-377370 P | 100 µg/0.5 ml | $69.00 |