Slac2-a Antibody (G-10): sc-515894
- Slac2-a Antibody (G-10) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 483-504 near the C-terminus of Slac2-a of human origin
- Anti-Slac2-a Antibody (G-10) is recommended for detection of Slac2-a of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Slac2-a Antibody (G-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Slac2-a Antibody (G-10) for WB applications. These reagents are now offered in bundles with Slac2-a Antibody (G-10) (see ordering information below).
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Slac2-a Antibody (G-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects Slac2-a in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Slac2-a antibody (G-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Slac2-a, or synaptotagmin-like protein (Slp) homolog lacking C2 domains-a, plays a crucial role in linking Rab27A on melanosomes with Myosin VA in melanocytes, facilitating transport of pigment and cytotoxic granules. Slac2-a features a synaptotagmin-like protein homology domain (SHD) near the N-terminus, which is essential for binding to GTP-bound Rab27A, while the C-terminal region interacts with Myosin VA. Stable formation of this complex is vital for proper cellular function, and mutations in the binding domains can lead to severe consequences, including albinism and immune disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Slac2-a Antibody (G-10) | sc-515894 | 200 µg/ml | $322.00 | |||
Slac2-a Antibody (G-10): m-IgG Fc BP-HRP Bundle | sc-528066 | 200 µg Ab; 10 µg BP | $361.00 | |||
Slac2-a Antibody (G-10): m-IgG1 BP-HRP Bundle | sc-533439 | 200 µg Ab; 20 µg BP | $361.00 | |||
Slac2-a Antibody (G-10) AC | sc-515894 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Slac2-a Antibody (G-10) HRP | sc-515894 HRP | 200 µg/ml | $322.00 | |||
Slac2-a Antibody (G-10) FITC | sc-515894 FITC | 200 µg/ml | $336.00 | |||
Slac2-a Antibody (G-10) PE | sc-515894 PE | 200 µg/ml | $349.00 | |||
Slac2-a Antibody (G-10) Alexa Fluor® 488 | sc-515894 AF488 | 200 µg/ml | $364.00 | |||
Slac2-a Antibody (G-10) Alexa Fluor® 546 | sc-515894 AF546 | 200 µg/ml | $364.00 | |||
Slac2-a Antibody (G-10) Alexa Fluor® 594 | sc-515894 AF594 | 200 µg/ml | $364.00 | |||
Slac2-a Antibody (G-10) Alexa Fluor® 647 | sc-515894 AF647 | 200 µg/ml | $364.00 | |||
Slac2-a Antibody (G-10) Alexa Fluor® 680 | sc-515894 AF680 | 200 µg/ml | $364.00 | |||
Slac2-a Antibody (G-10) Alexa Fluor® 790 | sc-515894 AF790 | 200 µg/ml | $364.00 |