SKAP55 Antibody (35): sc-136068
- SKAP55 Antibody (35) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
- raised against amino acids 154-353 of SKAP55 of human origin
- recommended for detection of SKAP55 of mouse, rat and human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SKAP55 Antibody (35). This work is in progress.
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SKAP55 Antibody (35) is a mouse monoclonal IgG1 antibody that detects SKAP55 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). SKAP55 plays a crucial role in T cell signaling by acting as a substrate for the tyrosine kinase p59fyn, which is essential for the activation of lymphocyte antigen receptors. SKAP55 is primarily located in the cytoplasm and is involved in the formation of signaling complexes that regulate T cell activation, making SKAP55 vital for immune responses. SKAP55 contains a pleckstrin homology domain at its N-terminus, which is important for membrane localization, and a C-terminal SH3 domain that facilitates interactions with other signaling proteins, including SLAP-130. These interactions are critical for the proper regulation of signaling pathways that lead to T cell activation, highlighting SKAP55′s importance in maintaining immune system functionality. The human SKAP55 gene is located on chromosome 17q21.32 and encodes a 359 amino acid protein, underscoring SKAP55′s evolutionary conservation and significance across species. Anti-SKAP55 antibody (35) is an invaluable tool for researchers studying T cell signaling and immune responses.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SKAP55 Antibody (35) | sc-136068 | 50 µg/0.5 ml | $322.00 |