SH-PTP2 Antibody (D-3): sc-271053
- SH-PTP2 Antibody (D-3) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 6-213 mapping within the amino terminal domain of SH-PTP2 of human origin
- recommended for detection of SH-PTP2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine and canine
- See SH-PTP2 (B-1): sc-7384 for SH-PTP2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SH-PTP2 Antibody (D-3) for WB and IHC(P) applications. These reagents are now offered in bundles with SH-PTP2 Antibody (D-3) (see ordering information below).
SH-PTP2 Antibody (D-3) is a mouse monoclonal IgG1 antibody that detects SH-PTP2 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). SH-PTP2, also known as PTP1D or Syp, plays a crucial role in cellular signaling by dephosphorylating tyrosine residues on proteins, thereby regulating various signaling pathways. SH-PTP2 is predominantly expressed in hematopoietic cells and is characterized by two SH2 domains that facilitate interaction with phosphotyrosine-containing substrates. These SH2 domains allow SH-PTP2 to bind to specific phosphorylated sites on receptors, influencing downstream signaling events vital for cell growth, differentiation, and immune responses. The structural similarity of SH-PTP2 to the Drosophila gene corkscrew suggests conserved functions across species, further emphasizing SH-PTP2′s importance in cellular regulation. As a significant target for research in understanding cancer and autoimmune disorders, anti-SH-PTP2 antibody (D-3) serves as an invaluable tool for studying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SH-PTP2 Antibody (D-3) | sc-271053 | 200 µg/ml | $322.00 | |||
SH-PTP2 Antibody (D-3): m-IgG Fc BP-HRP Bundle | sc-537564 | 200 µg Ab; 10 µg BP | $361.00 | |||
SH-PTP2 Antibody (D-3): m-IgGκ BP-HRP Bundle | sc-534863 | 200 µg Ab; 40 µg BP | $361.00 | |||
SH-PTP2 Antibody (D-3): m-IgG1 BP-HRP Bundle | sc-545231 | 200 µg Ab; 20 µg BP | $361.00 |