Date published: 2026-3-20

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SH-PTP Inhibitors

Santa Cruz Biotechnology now offers a broad range of SH-PTP inhibitors for use in various applications. SH-PTP inhibitors are a specialized class of chemicals designed to inhibit the activity of Src homology phosphotyrosine phosphatases (SH-PTP), enzymes that play a crucial role in cellular signaling pathways. These inhibitors are essential tools in the study of cellular processes, including cell growth, differentiation, and signal transduction. Researchers use SH-PTP inhibitors to dissect the functions of SH-PTPs in various biological systems, helping to study the mechanisms by which these enzymes regulate cellular behavior. The ability to selectively inhibit SH-PTPs allows scientists to understand better the pathways involved in cellular communication and regulation, providing insights into basic biological processes. Additionally, SH-PTP inhibitors are valuable in studying diseases where SH-PTP dysregulation is implicated, offering a clearer understanding of the underlying biological mechanisms. These compounds have become indispensable in laboratories focusing on biochemistry, molecular biology, and cell biology, contributing to the advancement of scientific knowledge in these fields. View detailed information on our available SH-PTP inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Suramin sodium

129-46-4sc-507209
sc-507209F
sc-507209A
sc-507209B
sc-507209C
sc-507209D
sc-507209E
50 mg
100 mg
250 mg
1 g
10 g
25 g
50 g
$152.00
$214.00
$728.00
$2601.00
$10965.00
$21838.00
$41096.00
5
(1)

Suramin sodium is a complex polysulfonated naphthylurea that exhibits unique interactions with various protein tyrosine phosphatases (PTPs). Its structure enables it to bind selectively to the active sites of SH-PTPs, modulating their activity through steric hindrance and electrostatic interactions. The compound's multi-site binding capability influences reaction kinetics, allowing for nuanced regulation of cellular signaling pathways. Its solubility and stability in aqueous environments further enhance its potential to interact with diverse biomolecular targets.