SgK269 Antibody (EB-8): sc-100403

SgK269 Antibody (EB-8) is a mouse monoclonal IgG2a kappa light chain antibody that detects SgK269 of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-SgK269 antibody (EB-8) is available as a non-conjugated format. SgK269, also known as sugen kinase 269, is a member of the NKF3 kinase family and consists of 1,746 amino acids, classifying SgK269 within the protein kinase superfamily. SgK269 plays a crucial role in cellular signaling pathways, particularly in the regulation of cell growth and survival, by acting as a protein tyrosine kinase. SgK269 phosphorylates specific tyrosine residues on target proteins, which can lead to the activation or inhibition of various signaling cascades. Such post-translational modifications are vital for proper functioning of cellular processes, including proliferation and differentiation, making SgK269 a significant player in both normal physiology and disease states. Anti-SgK269 antibody (EB-8) provides high specificity and sensitivity for researchers studying the intricate roles of protein kinases in human health and disease.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

SgK269 Antibody (EB-8) References:

1. Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method.  |  Ohara, O., et al. 2002. DNA Res. 9: 47-57. PMID: 12056414
2. The protein kinase complement of the human genome.  |  Manning, G., et al. 2002. Science. 298: 1912-34. PMID: 12471243
3. The mouse kinome: discovery and comparative genomics of all mouse protein kinases.  |  Caenepeel, S., et al. 2004. Proc Natl Acad Sci U S A. 101: 11707-12. PMID: 15289607
4. Purification and characterization of a protein-tyrosine kinase encoded by the Abelson murine leukemia virus.  |  Foulkes, JG., et al. 1985. J Biol Chem. 260: 8070-7. PMID: 2989275
5. Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.  |  Friedman, B., et al. 1984. Proc Natl Acad Sci U S A. 81: 3034-8. PMID: 6328489
6. Signalling by receptor tyrosine kinases.  |  Fantl, WJ., et al. 1993. Annu Rev Biochem. 62: 453-81. PMID: 7688944
7. Regulation of signal transduction and signal diversity by receptor oligomerization.  |  Lemmon, MA. and Schlessinger, J. 1994. Trends Biochem Sci. 19: 459-63. PMID: 7855887

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-SgK269 Antibody (EB-8) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-SgK269 Antibody (EB-8) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

SgK269 Antibody (EB-8) Specifications

Alternate Product Name: SgK269

Product Clone Name: EB-8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 1151-1250

Epitope Target: SgK269

Epitope Species: human

Product Reactivity/Detection: SgK269

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for SgK269 Antibody (EB-8): N/A