SETD5 Antibody (D-12): sc-515645
- SETD5 Antibody (D-12) is a mouse monoclonal IgG1 κ SETD5 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1341-1442 mapping at the C-terminus of SETD5 of human origin
- SETD5 Antibody (D-12) is recommended for detection of SETD5 of human origin by WB, IP, IF and ELISA
- Anti-SETD5 Antibody (D-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SETD5 Antibody (D-12) for WB applications. These reagents are now offered in bundles with SETD5 Antibody (D-12) (see ordering information below).
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SETD5 Antibody (D-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects SETD5 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-SETD5 antibody (D-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SETD5 plays a crucial role in the regulation of gene expression and is involved in chromatin remodeling, which is essential for maintaining genomic stability and proper cellular function. Mutations or dysregulation of SETD5 have been implicated in various developmental disorders and cancers, highlighting SETD5′s importance in cellular processes. SETD5 interacts with several key proteins, including transcriptional coactivator CBP and chromatin remodeling complex components, which further underscores SETD5′s role in modulating gene expression and maintaining cellular homeostasis. Understanding SETD5 function and interactions is vital for elucidating disease mechanisms and potential therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SETD5 Antibody (D-12) References:
- Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution. | Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
- [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification]. | Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
- Plasticity of human chromosome 3 during primate evolution. | Tsend-Ayush, E., et al. 2004. Genomics. 83: 193-202. PMID: 14706448
- Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2. | Yue, Y., et al. 2005. Cytogenet Genome Res. 108: 98-105. PMID: 15545721
- Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution. | Yue, Y., et al. 2005. Genomics. 85: 36-47. PMID: 15607420
- Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the 'elimination test'. | Darai, E., et al. 2005. Genomics. 86: 1-12. PMID: 15913951
- The DNA sequence, annotation and analysis of human chromosome 3. | Muzny, DM., et al. 2006. Nature. 440: 1194-8. PMID: 16641997
- Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3. | Nareyeck, G., et al. 2006. Exp Eye Res. 83: 858-64. PMID: 16750193
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SETD5 Antibody (D-12) | sc-515645 | 200 µg/ml | $322.00 | |||
SETD5 Antibody (D-12): m-IgG Fc BP-HRP Bundle | sc-531452 | 200 µg Ab; 10 µg BP | $361.00 | |||
SETD5 Antibody (D-12): m-IgGκ BP-HRP Bundle | sc-525144 | 200 µg Ab, 40 µg BP | $361.00 | |||
SETD5 Antibody (D-12): m-IgG1 BP-HRP Bundle | sc-544565 | 200 µg Ab; 20 µg BP | $361.00 | |||
SETD5 Antibody (D-12) AC | sc-515645 AC | 500 µg/ml, 25% agarose | $424.00 | |||
SETD5 Antibody (D-12) HRP | sc-515645 HRP | 200 µg/ml | $322.00 | |||
SETD5 Antibody (D-12) FITC | sc-515645 FITC | 200 µg/ml | $336.00 | |||
SETD5 Antibody (D-12) PE | sc-515645 PE | 200 µg/ml | $349.00 | |||
SETD5 Antibody (D-12) Alexa Fluor® 488 | sc-515645 AF488 | 200 µg/ml | $364.00 | |||
SETD5 Antibody (D-12) Alexa Fluor® 546 | sc-515645 AF546 | 200 µg/ml | $364.00 | |||
SETD5 Antibody (D-12) Alexa Fluor® 594 | sc-515645 AF594 | 200 µg/ml | $364.00 | |||
SETD5 Antibody (D-12) Alexa Fluor® 647 | sc-515645 AF647 | 200 µg/ml | $364.00 | |||
SETD5 Antibody (D-12) Alexa Fluor® 680 | sc-515645 AF680 | 200 µg/ml | $364.00 | |||
SETD5 Antibody (D-12) Alexa Fluor® 790 | sc-515645 AF790 | 200 µg/ml | $364.00 |