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Sds22 Antibody (B-8): sc-398865

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Datasheets
  • Sds22 Antibody (B-8) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 58-87 within an internal region of Sds22 of human origin
  • recommended for detection of Sds22 of human origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Sds22 Antibody (B-8) for WB applications. These reagents are now offered in bundles with Sds22 Antibody (B-8) (see ordering information below).

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    Sds22 Antibody (B-8) is a mouse monoclonal IgG2a antibody that detects Sds22 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a crucial regulatory component of the protein phosphatase 1 (PP1) holoenzyme, which plays a significant role in cellular processes by modulating the phosphorylation state of various substrates. This 360 amino acid protein is primarily localized in the nucleus and features ten leucine-rich repeats, which are important for protein-protein interactions and stability. The presence of multiple isoforms of Sds22, resulting from alternative splicing, highlights its versatility and potential for diverse regulatory functions within the cell. By participating in the assembly and regulation of the PP1 complex, Sds22 is integral to maintaining cellular homeostasis, influencing processes such as cell division and apoptosis, making Sds22 a vital target for research in cellular signaling pathways and disease mechanisms. Anti-Sds22 antibody (B-8) is an essential tool for researchers aiming to explore the intricate roles of Sds22 in various biological contexts.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Sds22 Antibody (B-8)

    sc-398865
    200 µg/ml
    $316.00

    Sds22 Antibody (B-8): m-IgG Fc BP-HRP Bundle

    sc-538531
    200 µg Ab; 10 µg BP
    $354.00

    Sds22 Antibody (B-8): m-IgGκ BP-HRP Bundle

    sc-536162
    200 µg Ab; 40 µg BP
    $354.00

    Sds22 Antibody (B-8): m-IgG2a BP-HRP Bundle

    sc-548334
    200 µg Ab; 10 µg BP
    $354.00

    Sds22 (B-8) Neutralizing Peptide

    sc-398865 P
    100 µg/0.5 ml
    $68.00

    We are looking for a replacement antibody for the polyclonal SDS22 antibody. We already tried sc-398864 which did not yield good results and we would like to test this antibody (sc-398865). Is it possible to request a test sample?

    Asked by: ZC LBT
    Thank you for your question. If you have an interest in testing a sample, please contact our Technical Service by email (europe@scbt.com) or phone (00800 4573 8000).
    Answered by: Technical Support Europe
    Date published: 2017-12-15

    What application is the blocking peptide sc-398865 P appropriate for?

    Asked by: jenniferc
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2025, m_9, d_25, h_5CST
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    Rated 3 out of 5 by from Good WB result, no IPWe tried this antibody as a replacement for the polyclonal anti-SDS22 E-20 and achieved comparable WB results at 1:1000 dilution. However, we could not enrich the target protein in comparable amounts as with the polyclonal Ab.
    Date published: 2017-10-30
    Rated 5 out of 5 by from Very good Western blot data of Sds22 expressionVery good Western blot data of Sds22 expression in K-562 nuclear extract and c4, PC-3, K-562, IMR-32 and HeLa whole cell lysates. -SCBT QC
    Date published: 2013-10-04
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    Sds22 Antibody (B-8) is rated 4.0 out of 5 by 2.
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