SBNO1 Antibody (A-5): sc-166519
- SBNO1 Antibody (A-5) is a mouse monoclonal IgG2b κ SBNO1 antibody provided at 200 µg/ml
- raised against amino acids 1-240 mapping at the N-terminus of SBNO1 of human origin
- SBNO1 Antibody (A-5) is recommended for detection of SBNO1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-SBNO1 Antibody (A-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-166519 X, 200 µg/0.1 ml)
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of SBNO1 (A-5): sc-166519.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SBNO1 Antibody (A-5). This work is in progress.
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SBNO1 Antibody (A-5) is a mouse monoclonal IgG2b kappa light chain antibody that detects SBNO1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SBNO1 (A-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SBNO1, also known as strawberry notch homolog 1, is a 1,392 amino acid protein encoded by the human gene located on chromosome 12, which plays a critical role in regulating gene expression during development. SBNO1 is essential for proper cellular differentiation and morphogenesis, as SBNO1 is involved in the Notch signaling pathway, which is crucial for cell fate determination and tissue patterning. Dysregulation of SBNO1 has been implicated in various developmental disorders, highlighting SBNO1′s importance in maintaining normal physiological processes. Chromosome 12, where SBNO1 gene resides, is associated with several genetic conditions, including skeletal deformities and developmental syndromes, underscoring SBNO1′s significance in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SBNO1 Antibody (A-5) References:
- The genomic context of natural killer receptor extended gene families. | Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
- Genotype/phenotype analysis in a patient with pure and complete trisomy 12p. | Zumkeller, W., et al. 2004. Am J Med Genet A. 129A: 261-4. PMID: 15326625
- The phenotypic spectrum of COL2A1 mutations. | Nishimura, G., et al. 2005. Hum Mutat. 26: 36-43. PMID: 15895462
- Comparative genomics of natural killer cell receptor gene clusters. | Kelley, J., et al. 2005. PLoS Genet. 1: 129-39. PMID: 16132082
- The natural history of trisomy 12p. | Segel, R., et al. 2006. Am J Med Genet A. 140: 695-703. PMID: 16502429
- Noonan syndrome. | van der Burgt, I. 2007. Orphanet J Rare Dis. 2: 4. PMID: 17222357
- Cytogenetic and molecular analysis in trisomy 12p. | Allen, TL., et al. 1996. Am J Med Genet. 63: 250-6. PMID: 8723118
- Low basal transcripts of the COL2A1 collagen gene from lymphoblasts show alternative splicing of exon 12 in the Kniest form of spondyloepiphyseal dysplasia. | Yang, W. and Cole, WG. 1998. Hum Mutat. Suppl 1: S1-2. PMID: 9452022
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SBNO1 Antibody (A-5) | sc-166519 | 200 µg/ml | $316.00 | |||
SBNO1 Antibody (A-5) X | sc-166519 X | 200 µg/0.1 ml | $316.00 | |||
SBNO1 Antibody (A-5) AC | sc-166519 AC | 500 µg/ml, 25% agarose | $416.00 | |||
SBNO1 Antibody (A-5) HRP | sc-166519 HRP | 200 µg/ml | $316.00 | |||
SBNO1 Antibody (A-5) FITC | sc-166519 FITC | 200 µg/ml | $330.00 | |||
SBNO1 Antibody (A-5) PE | sc-166519 PE | 200 µg/ml | $343.00 | |||
SBNO1 Antibody (A-5) Alexa Fluor® 488 | sc-166519 AF488 | 200 µg/ml | $357.00 | |||
SBNO1 Antibody (A-5) Alexa Fluor® 546 | sc-166519 AF546 | 200 µg/ml | $357.00 | |||
SBNO1 Antibody (A-5) Alexa Fluor® 594 | sc-166519 AF594 | 200 µg/ml | $357.00 | |||
SBNO1 Antibody (A-5) Alexa Fluor® 647 | sc-166519 AF647 | 200 µg/ml | $357.00 | |||
SBNO1 Antibody (A-5) Alexa Fluor® 680 | sc-166519 AF680 | 200 µg/ml | $357.00 | |||
SBNO1 Antibody (A-5) Alexa Fluor® 790 | sc-166519 AF790 | 200 µg/ml | $357.00 |