Sall4 Antibody (G-3): sc-166033
- Sall4 Antibody (G-3) is a mouse monoclonal IgG1 κ Sall4 antibody, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1017-1053 at the C-terminus of Sall4 of human origin
- Sall4 Antibody (G-3) is recommended for detection of Sall4 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine and porcine
- TransCruz reagent for ChIP application (sc-166033 X, 200 µg/0.1 ml)
- Anti-Sall4 Antibody (G-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Sall4 Antibody (G-3) for WB applications. These reagents are now offered in bundles with Sall4 Antibody (G-3) (see ordering information below).
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Sall4 Antibody (G-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects Sall4 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Sall4 antibody (G-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. Sall4 protein plays a crucial role in early embryonic development and is essential for maintaining pluripotency in stem cells, making Sall4 a significant marker in developmental biology and regenerative medicine. Sall4 expression is tightly regulated during development, and aberrations in Sall4 levels can lead to developmental disorders and contribute to tumorigenesis. Sall4 protein is primarily localized in the nucleus, where Sall4 functions as a transcription factor, interacting with other proteins to regulate gene expression critical for cell fate determination. Understanding Sall4 dynamics and interactions is vital for elucidating mechanisms underlying stem cell biology and developmental processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Sall4 Antibody (G-3) References:
- SALL4, the missing link between stem cells, development and cancer. | Tatetsu, H., et al. 2016. Gene. 584: 111-9. PMID: 26892498
- Oncofetal gene SALL4 and prognosis in cancer: A systematic review with meta-analysis. | Nicolè, L., et al. 2017. Oncotarget. 8: 22968-22979. PMID: 28160555
- SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis. | Yang, J. 2018. Biomark Res. 6: 1. PMID: 29308206
- Oncofetal SALL4-Driven Tumorigenesis Is Highly Dependent on Oxidative Phosphorylation, Revealing Therapeutic Opportunities. | Liu, T. and Shyh-Chang, N. 2019. Gastroenterology. 157: 1475-1477. PMID: 31606470
- SALL4 Oncogenic Function in Cancers: Mechanisms and Therapeutic Relevance. | Sun, B., et al. 2022. Int J Mol Sci. 23: PMID: 35216168
- Potential application of human SALL4 on oral squamous cell carcinoma. | Matos, LL. and da Silva, JB. 2022. Ann Transl Med. 10: 919. PMID: 36172107
- The NuRD complex cooperates with SALL4 to orchestrate reprogramming. | Wang, B., et al. 2023. Nat Commun. 14: 2846. PMID: 37208322
- The new advance of SALL4 in cancer: Function, regulation, and implication. | Abouelnazar, FA., et al. 2023. J Clin Lab Anal. 37: e24927. PMID: 37337914
- SALL4 promotes cancer stem-like cell phenotype and radioresistance in oral squamous cell carcinomas via methyltransferase-like 3-mediated m6A modification. | Huang, J., et al. 2024. Cell Death Dis. 15: 139. PMID: 38355684
- SALL4 in gastrointestinal tract cancers: upstream and downstream regulatory mechanisms. | Wang, T., et al. 2024. Mol Med. 30: 46. PMID: 38584262
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sall4 Antibody (G-3) | sc-166033 | 200 µg/ml | $322.00 | |||
Sall4 Antibody (G-3): m-IgG Fc BP-HRP Bundle | sc-528896 | 200 µg Ab; 10 µg BP | $361.00 | |||
Sall4 Antibody (G-3): m-IgGκ BP-HRP Bundle | sc-521490 | 200 µg Ab, 40 µg BP | $361.00 | |||
Sall4 Antibody (G-3): m-IgG1 BP-HRP Bundle | sc-543199 | 200 µg Ab; 20 µg BP | $361.00 | |||
Sall4 Antibody (G-3) X | sc-166033 X | 200 µg/0.1 ml | $322.00 | |||
Sall4 Antibody (G-3) AC | sc-166033 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Sall4 Antibody (G-3) HRP | sc-166033 HRP | 200 µg/ml | $322.00 | |||
Sall4 Antibody (G-3) FITC | sc-166033 FITC | 200 µg/ml | $336.00 | |||
Sall4 Antibody (G-3) PE | sc-166033 PE | 200 µg/ml | $349.00 | |||
Sall4 Antibody (G-3) Alexa Fluor® 488 | sc-166033 AF488 | 200 µg/ml | $364.00 | |||
Sall4 Antibody (G-3) Alexa Fluor® 546 | sc-166033 AF546 | 200 µg/ml | $364.00 | |||
Sall4 Antibody (G-3) Alexa Fluor® 594 | sc-166033 AF594 | 200 µg/ml | $364.00 | |||
Sall4 Antibody (G-3) Alexa Fluor® 647 | sc-166033 AF647 | 200 µg/ml | $364.00 | |||
Sall4 Antibody (G-3) Alexa Fluor® 680 | sc-166033 AF680 | 200 µg/ml | $364.00 | |||
Sall4 Antibody (G-3) Alexa Fluor® 790 | sc-166033 AF790 | 200 µg/ml | $364.00 | |||
Sall4 (G-3) Neutralizing Peptide | sc-166033 P | 100 µg/0.5 ml | $69.00 |