RT1-A Antibody (6A443): sc-71973

RT1-A Antibody (6A443) is a mouse monoclonal IgG1 antibody that detects RT1-A in mouse and rat samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). RT1-A is crucial for the immune system as RT1-A (6A443) antibody plays a significant role in presenting nonself peptides to cytotoxic T-lymphocytes, thereby facilitating the recognition and elimination of infected or malignant cells. The structure of RT1-A consists of two polypeptide chains: an alpha or heavy chain and beta-2-microglobulin, which together form a stable complex essential for effective antigen presentation. The peptide binding groove of RT1-A is specifically designed to accommodate antigenic peptides typically 8-10 residues in length, ensuring appropriate antigens are presented to T-lymphocytes. This precise structural configuration is vital for the immune response, as RT1-A determines the specificity and efficiency of T-cell activation, ultimately influencing the body′s ability to combat infections and tumors. Anti-RT1-A antibody (6A443) serves as an invaluable tool for researchers studying immune responses and mechanisms of antigen presentation in various biological contexts.

The preferred RT1-A antibody is RT1-A Antibody (OX18): sc-53074.