RT1-A Antibody (3H2655): sc-71972

RT1-A Antibody (3H2655) is a mouse monoclonal IgG1 antibody that detects RT1-A in mouse and rat samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Anti-RT1-A antibody (3H2655) plays a crucial role in the immune response by presenting nonself peptides on the cell surface, which are essential for recognition by cytotoxic T-lymphocytes (CTLs). RT1-A molecules consist of class Ia and class Ib molecules, which are composed of two polypeptide chains: an alpha or heavy chain and beta-2-Microglobulin, a non-covalently associated protein. The structure of RT1-A allows for the binding of antigenic peptides, typically 8-10 residues in length, within a specialized peptide binding groove. This structural feature facilitates effective presentation of antigens to CTLs and ensures accurate distinction between self and nonself entities, maintaining immune homeostasis and preventing autoimmune responses. RT1-A′s ability to present diverse peptides is critical for adaptive immune response, making RT1-A (3H2655) monoclonal antibody an invaluable tool for researchers studying immune mechanisms and T-cell activation.

The preferred RT1-A antibody is RT1-A Antibody (OX18): sc-53074.