RPA 14 kDa subunit Antibody (A-2): sc-393891

RPA 14 kDa subunit Antibody (A-2) is a mouse monoclonal IgG2a kappa light chain antibody that detects the RPA 14 kDa subunit protein of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RPA 14 kDa subunit (A-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RPA 14 kDa subunit, also known as RPA3, is a critical component of the replication protein A complex, which is essential for DNA replication, recombination, and repair in eukaryotic cells. RPA3 is primarily located in the nucleus, where RPA3 plays a vital role in maintaining genomic stability by binding to single-stranded DNA during DNA damage recognition and repair. The RPA complex, consisting of 14 kDa, 32 kDa, and 70 kDa subunits, acts as a scaffold for recruiting other proteins involved in DNA metabolism, facilitating the coordination of various repair pathways. RPA3′s ability to interact with other proteins, such as RAD51 and BRCA1, underscores RPA3′s importance in homologous recombination and cellular response to DNA damage, making RPA3 a key player in maintaining genome integrity.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-RPA 14 kDa subunit Antibody (A-2) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-RPA 14 kDa subunit Antibody (A-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

RPA 14 kDa subunit Antibody (A-2) Specifications

Alternate Product Name: RPA 14 kDa subunit

Product Clone Name: A-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 96-121

Epitope Target: RPA 14 kDa subunit

Epitope Species: mouse

Product Reactivity/Detection: RPA 14 kDa subunit

Species Reactivity/Detection: mouse

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for RPA 14 kDa subunit Antibody (A-2): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin, X: TransCruz Reagent

The preferred RPA 14 kDa subunit antibody is RPA 14 kDa subunit Antibody (E-2): sc-271564.