RIA1 Antibody (A-7): sc-514617

RIA1 Antibody (A-7) is a mouse monoclonal IgG1 antibody that detects RIA1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RIA1, also known as EFTUD1 or FAM42A, is a crucial protein involved in ribosome assembly, playing a significant role in protein synthesis within cells. Anti-RIA1 antibody (A-7) supports research in cellular function and growth, as ribosomes are the machinery that translates messenger RNA into polypeptides, which ultimately fold into functional proteins. The proper assembly and function of ribosomes are essential for maintaining cellular homeostasis and responding to stress, and any disruption in this process can lead to various diseases, including neurodevelopmental disorders. RIA1 exists as three alternatively spliced isoforms and is encoded by a gene located on human chromosome 15, a region associated with several genetic disorders, including Angelman and Prader-Willi syndromes, which arise from deletions or mutations affecting gene expression in this chromosomal region. RIA1 (A-7) antibody is an invaluable tool for researchers studying ribosome biogenesis and its implications in health and disease.

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RIA1 Antibody (A-7) References:

1. Novel Fc gamma receptor I family gene products in human mononuclear cells.  |  Porges, AJ., et al. 1992. J Clin Invest. 90: 2102-9. PMID: 1430234
2. Evaluation of immunoassays for the measurement of insulin-like growth factor-I and procollagen type III peptide, indirect biomarkers of recombinant human growth hormone misuse in sport.  |  Abellan, R., et al. 2005. Clin Chem Lab Med. 43: 75-85. PMID: 15653447
3. [125I]N6-(3-iodo-4-hydroxyphenyl)isopropyladenosine: the use of the diastereomers as ligands for adenosine receptors in rat brain.  |  Munshi, R., et al. 1985. Eur J Pharmacol. 111: 107-15. PMID: 2990937
4. Sirt6 ablation in the liver causes fatty liver that increases cancer risky by upregulating Serpina12.  |  Li, L., et al. 2024. EMBO Rep. 25: 1361-1386. PMID: 38332150
5. Tyrosinase-Woven Melanin Nets for Melanoma Therapy through Targeted Mitochondrial Tethering and Enhanced Photothermal Treatment.  |  Tang, M., et al. 2024. Adv Mater. 36: e2411906. PMID: 39285827
6. Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery.  |  Wang, W., et al. 2024. Nat Commun. 15: 10804. PMID: 39738043
7. Towards simplified graph neural networks for identifying cancer driver genes in heterophilic networks.  |  Li, X., et al. 2024. Brief Bioinform. 26: PMID: 39751645
8. Manganese Galvanic Cells Intervene in Tumor Metabolism to Reinforce cGAS-STING Activation for Bidirectional Synergistic Hydrogen-Immunotherapy.  |  Yang, N., et al. 2025. Adv Mater. 37: e2414929. PMID: 39775989
9. Recombinant CD80 fusion protein combined with discoidin domain receptor 1 inhibitor for cancer treatment.  |  Wang, S., et al. 2025. Appl Microbiol Biotechnol. 109: 39. PMID: 39918582
10. Hypercalcemia in hyperthyroidism. Role of age and goiter type.  |  Szabó, ZS. and Ritzl, F. 1981. Klin Wochenschr. 59: 275-9. PMID: 7230726

The preferred RIA1 antibody is RIA1 Antibody (C-5): sc-398435.