Date published: 2026-5-6

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Rent3 Antibody (C-2): sc-398820

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Datasheets
  • Rent3 Antibody (C-2) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
  • raised against amino acids 51-240 mapping near the N-terminus of Rent3b of human origin
  • recommended for detection of Rent3a and Rent3b of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine
  • TransCruz reagent for ChIP application (sc-398820 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Rent3 Antibody (C-2) for WB applications. These reagents are now offered in bundles with Rent3 Antibody (C-2) (see ordering information below).
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    Rent3 Antibody (C-2) is a mouse monoclonal IgG2a antibody that detects Rent3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rent3, also known as Rent3a and Rent3b, plays a crucial role in the nonsense-mediated RNA decay (NMD) pathway, which maintains cellular integrity by preventing the accumulation of faulty transcripts that could lead to truncated and potentially harmful proteins. Rent3 is primarily localized in the nucleus, where Rent3 interacts with spliced mRNA and other proteins, such as Y14, to facilitate the connection between mRNA splicing and NMD. Proper functioning of Rent3 is essential for embryonic development and cellular homeostasis, as Rent3 helps ensure that only fully functional mRNAs are translated into proteins. Additionally, Rent3b, which is encoded by an X-linked gene, localizes to the nucleus and is involved in the regulation of gene expression. anti-Rent3 antibody (C-2) is an invaluable tool for researchers studying RNA metabolism and the mechanisms underlying gene regulation, providing insights into the complex interplay between splicing and mRNA decay.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Rent3 Antibody (C-2)

    sc-398820
    200 µg/ml
    $322.00

    Rent3 Antibody (C-2): m-IgG Fc BP-HRP Bundle

    sc-538528
    200 µg Ab; 10 µg BP
    $361.00

    Rent3 Antibody (C-2): m-IgGκ BP-HRP Bundle

    sc-536156
    200 µg Ab; 40 µg BP
    $361.00

    Rent3 Antibody (C-2): m-IgG2a BP-HRP Bundle

    sc-548331
    200 µg Ab; 10 µg BP
    $361.00

    Rent3 Antibody (C-2) X

    sc-398820 X
    200 µg/0.1 ml
    $322.00

    How much sample do you recommend loading on the gel for Western blot detection using Rent3 (C-2): sc-398820?

    Asked by: DefinitelyNotMatt
    We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2026, m_5, d_6, h_12CST
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    Rated 5 out of 5 by from Satisfactory Western blot data of Rent3bSatisfactory Western blot data of Rent3b expression in non-transfected 293T, mouse Rent3b transfected 293T HeLa, Jurkat and K-562 whole cell lysates. -SCBT QC
    Date published: 2013-12-24
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    Rent3 Antibody (C-2) is rated 5.0 out of 5 by 1.
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