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Rent3 Antibody (C-2) is a mouse monoclonal IgG2a antibody that detects Rent3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rent3, also known as Rent3a and Rent3b, plays a crucial role in the nonsense-mediated RNA decay (NMD) pathway, which maintains cellular integrity by preventing the accumulation of faulty transcripts that could lead to truncated and potentially harmful proteins. Rent3 is primarily localized in the nucleus, where Rent3 interacts with spliced mRNA and other proteins, such as Y14, to facilitate the connection between mRNA splicing and NMD. Proper functioning of Rent3 is essential for embryonic development and cellular homeostasis, as Rent3 helps ensure that only fully functional mRNAs are translated into proteins. Additionally, Rent3b, which is encoded by an X-linked gene, localizes to the nucleus and is involved in the regulation of gene expression. anti-Rent3 antibody (C-2) is an invaluable tool for researchers studying RNA metabolism and the mechanisms underlying gene regulation, providing insights into the complex interplay between splicing and mRNA decay.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rent3 Antibody (C-2) | sc-398820 | 200 µg/ml | $322.00 | |||
Rent3 Antibody (C-2): m-IgG Fc BP-HRP Bundle | sc-538528 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rent3 Antibody (C-2): m-IgGκ BP-HRP Bundle | sc-536156 | 200 µg Ab; 40 µg BP | $361.00 | |||
Rent3 Antibody (C-2): m-IgG2a BP-HRP Bundle | sc-548331 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rent3 Antibody (C-2) X | sc-398820 X | 200 µg/0.1 ml | $322.00 |