Rent2 Antibody (G-9): sc-398812
- Rent2 Antibody (G-9) is a mouse monoclonal IgG2a (lambda light chain) provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1247-1273 near the C-terminus of Rent2 of human origin
- recommended for detection of Rent2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for Rent2 Antibody (G-9) for WB applications. These reagents are now offered in bundles with Rent2 Antibody (G-9) (see ordering information below).
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Rent2 Antibody (G-9) is a mouse monoclonal IgG2a antibody that detects Rent2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rent2, also known as the mammalian homolog of Upf2p, plays a crucial role in the nonsense-mediated RNA decay (NMD) pathway, which maintains cellular integrity by preventing the accumulation of faulty mRNA transcripts that could lead to truncated or malfunctioning proteins. Rent2 is primarily localized in the cytoplasm, where Rent2 interacts with Rent1 and Rent3 proteins, forming a complex essential for efficient degradation of defective mRNA. This localization allows Rent2 to effectively participate in mRNA quality surveillance, ensuring only properly processed transcripts are translated into functional proteins. The interaction of Rent2 with Rent1 and Rent3 highlights Rent2′s importance in linking splicing and NMD, safeguarding the cell from potential damage caused by aberrant protein synthesis. anti-Rent2 antibody (G-9) is an invaluable tool for researchers studying RNA metabolism and gene expression regulation mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rent2 Antibody (G-9) | sc-398812 | 200 µg/ml | $322.00 | |||
Rent2 Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-540947 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rent2 Antibody (G-9): m-IgG2a BP-HRP Bundle | sc-546986 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rent2 (G-9) Neutralizing Peptide | sc-398812 P | 100 µg/0.5 ml | $69.00 |