RD3 Antibody (B-10): sc-376800
- RD3 Antibody (B-10) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 145-175 within an internal region of RD3 of human origin
- recommended for detection of RD3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for RD3 Antibody (B-10) for WB applications. These reagents are now offered in bundles with RD3 Antibody (B-10) (see ordering information below).
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SEE ALSO...
RD3 Antibody (B-10) is a mouse monoclonal IgG2b antibody that detects RD3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RD3, also known as retinal degeneration 3 or LCA12, is a crucial 195 amino acid protein predominantly expressed in the retina, where RD3 plays a significant role in forming subnuclear protein complexes essential for various cellular processes, including transcription and splicing. Proper functioning of RD3 is vital for maintaining photoreceptor health and function; defects in RD3 lead to Leber congenital amaurosis type 12, a severe condition characterized by minimal or absent retinal photoreceptor activity in affected infants. This condition underscores RD3′s importance in visual development and potential for targeted therapeutic strategies aimed at restoring RD3 function. Anti-RD3 antibody (B-10) is an invaluable tool for researchers investigating molecular mechanisms underlying hereditary blindness.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RD3 Antibody (B-10) | sc-376800 | 200 µg/ml | $322.00 | |||
RD3 Antibody (B-10): m-IgGκ BP-HRP Bundle | sc-535514 | 200 µg Ab; 40 µg BP | $361.00 | |||
RD3 Antibody (B-10): m-IgG2b BP-HRP Bundle | sc-549439 | 200 µg Ab; 10 µg BP | $361.00 | |||
RD3 (B-10) Neutralizing Peptide | sc-376800 P | 100 µg/0.5 ml | $69.00 |