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Ran BP-M Antibody (A-5): sc-271726

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Datasheets
  • Ran BP-M Antibody (A-5) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 345-371 near the N-terminus of Ran BP-M of human origin
  • recommended for detection of Ran BP-M isoform 1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ran BP-M Antibody (A-5). This work is in progress.

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    Ran BP-M Antibody (A-5) is a mouse monoclonal IgG2a antibody that detects Ran BP-M in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Ran BP-M, also known as Ran-binding protein 9, plays a crucial role in microtubule network nucleation and serves as an adapter protein linking membrane receptors to intracellular signaling pathways, vital for cellular communication and response to external stimuli. Ran BP-M (A-5) antibody has been instrumental in studying hormone signaling, as Ran BP-M has been implicated in androgen and glucocorticoid receptor activation, influencing processes such as cell growth and differentiation. Ran BP-M contains phosphorylated serine residues, which affect localization and function; notably, phosphorylated Ran BP-M can associate with plasma membrane, highlighting a dynamic role in cellular signaling. Ran BP-M shows highest expression in heart, testis, muscle, and placenta, and anti-Ran BP-M antibody (A-5) has helped reveal enzymatic activity linked to significant health conditions, including breast cancer progression and fragile-X mental retardation. Ran BP-M (A-5) monoclonal antibody serves as an essential tool for researchers studying these critical biological processes and their implications in health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Ran BP-M Antibody (A-5)

    sc-271726
    200 µg/ml
    $316.00

    Ran BP-M (A-5) Neutralizing Peptide

    sc-271726 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-271726 P appropriate for?

    Asked by: jerojero
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-25
    • y_2025, m_9, d_17, h_8CST
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    Rated 5 out of 5 by from Excellent immunoperoxidase cytoplasmic stainingExcellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human heart muscle tissue. -SCBT QC
    Date published: 2015-03-30
    Rated 5 out of 5 by from Satisfactory Western Blot data of Ran BPSatisfactory Western Blot data of Ran BP-M expression in U-2 OS whole cell lysate. -SCBT QC
    Date published: 2013-10-13
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    Ran BP-M Antibody (A-5) is rated 5.0 out of 5 by 2.
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