RAI3 Antibody (F-3): sc-373824

RAI3 Antibody (F-3) is a mouse monoclonal IgG1 antibody that detects retinoic acid-induced protein 3 (RAI3) in human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RAI3 is a transmembrane G-protein-coupled receptor that plays a crucial role in various biological processes, including embryogenesis, cell growth, differentiation, and apoptosis, making RAI3 essential for normal cellular function and development. RAI3 is primarily located in the cell membrane, where RAI3 facilitates communication between the extracellular environment and intracellular signaling pathways, thus influencing cellular responses to external stimuli. Notably, RAI3 expression is often upregulated in tumor cell lines harboring mutant p53, indicating a potential interaction between p53 and RAI3 promoter that may repress expression during early stages of apoptosis. This regulatory mechanism highlights RAI3′s importance in maintaining cellular homeostasis and potential as a molecular target for breast cancer diagnosis and treatment, as selective modulation of RAI3 signaling could provide therapeutic avenues in oncology. Anti-RAI3 antibody (F-3) is an invaluable tool for researchers investigating RAI3′s role in cancer biology and other physiological processes.

The preferred RAI3 antibody is RAI3 Antibody (A-11): sc-390263.