RAGE Antibody (9A11): sc-80653
- RAGE Antibody (9A11) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 22-342 of RAGE of human origin
- recommended for detection of RAGE of human origin by WB, IP, IF and IHC(P)
- See RAGE (A-9): sc-365154 for RAGE antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for RAGE Antibody (9A11) for WB and IHC(P) applications. These reagents are now offered in bundles with RAGE Antibody (9A11) (see ordering information below).
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SEE ALSO...
RAGE Antibody (9A11) is a mouse monoclonal IgG1 kappa kappa light chain antibody engineered to recognize the human Receptor for Advanced Glycation End Products (RAGE) by targeting amino acids 22-342 of the protein. RAGE is a pivotal type I membrane protein predominantly located on the cell surface of endothelial cells, mononuclear phagocytes, and vascular smooth muscle cells, where it serves as a critical mediator of cellular responses to advanced glycation end products (AGEs) and other ligands. The strategic localization of RAGE on the cell membrane facilitates its role in transmitting extracellular signals into the cell, thereby activating pathways that lead to the production of reactive oxygen species and the activation of the transcription factor NF-κB. This activation is essential in regulating inflammatory responses, cellular proliferation, and apoptosis, making RAGE a key player in the development and progression of various pathological conditions such as diabetes, vascular diseases, and amyloidosis. RAGE (9A11) monoclonal antibody is specifically recommended for the detection of human RAGE in applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). RAGE (9A11) antibody is an invaluable tool for researchers investigating the intricate mechanisms of RAGE-mediated signaling pathways and their implications in disease mechanisms and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RAGE Antibody (9A11) | sc-80653 | 200 µg/ml | $322.00 | |||
RAGE Antibody (9A11): m-IgG Fc BP-HRP Bundle | sc-539571 | 200 µg Ab; 10 µg BP | $361.00 | |||
RAGE Antibody (9A11): m-IgG1 BP-HRP Bundle | sc-541565 | 200 µg Ab; 20 µg BP | $361.00 |