Rab GDI α Antibody (C-7): sc-271846
- Rab GDI α Antibody (C-7) is a mouse monoclonal IgG1 κ Rab GDI α antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 29-59 near the N-terminus of Rab GDI α of human origin
- Rab GDI alpha Antibody (C-7) is recommended for detection of Rab GDI α of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine
- Anti-Rab GDI alpha Antibody (C-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Rab GDI α Antibody (C-7) for WB applications. These reagents are now offered in bundles with Rab GDI α Antibody (C-7) (see ordering information below).
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Rab GDI α Antibody (C-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects Rab GDI alpha protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Rab GDI α antibody (C-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Rab GDI alpha protein plays a crucial role in intracellular vesicle trafficking by forming a soluble complex with Rab proteins, which prevents the exchange of guanosine diphosphate for guanosine triphosphate, thereby regulating the activation state of these small GTP-binding proteins. Notably, Rab GDI alpha is predominantly expressed in neural and sensory tissues, suggesting specific involvement in neural signal transmission, which is vital for proper communication between neurons and the processing of sensory information. Gene sequences for Rab GDI proteins are highly conserved across evolution, indicating essential function in cellular processes. Rab GDI α monoclonal antibody (C-7) serves as an invaluable tool for researchers studying vesicle trafficking and neural signaling pathways in various species.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Rab GDI α Antibody (C-7) References:
- The amphioxus rab GDP-dissociation inhibitor (GDI) gene is neural-specific: implications for the evolution of chordate rab GDI genes. | Sedlacek, Z., et al. 1999. Mol Biol Evol. 16: 1231-7. PMID: 10486978
- Expression patterns of two human genes coding for different rab GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport. | Bächner, D., et al. 1995. Hum Mol Genet. 4: 701-8. PMID: 7543319
- Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens. | Nishimura, N., et al. 1995. Cancer Res. 55: 5445-50. PMID: 7585614
- Purification and characterization of Rab GDI beta from rat brain. | Araki, K., et al. 1995. Biochem Biophys Res Commun. 211: 296-305. PMID: 7779099
- Molecular cloning and characterization of two rab GDI species from rat brain: brain-specific and ubiquitous types. | Nishimura, N., et al. 1994. J Biol Chem. 269: 14191-8. PMID: 8188702
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rab GDI α Antibody (C-7) | sc-271846 | 200 µg/ml | $322.00 | |||
Rab GDI α Antibody (C-7): m-IgG Fc BP-HRP Bundle | sc-527300 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rab GDI α Antibody (C-7): m-IgG1 BP-HRP Bundle | sc-532673 | 200 µg Ab; 20 µg BP | $361.00 | |||
Rab GDI α Antibody (C-7) AC | sc-271846 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Rab GDI α Antibody (C-7) HRP | sc-271846 HRP | 200 µg/ml | $322.00 | |||
Rab GDI α Antibody (C-7) FITC | sc-271846 FITC | 200 µg/ml | $336.00 | |||
Rab GDI α Antibody (C-7) PE | sc-271846 PE | 200 µg/ml | $349.00 | |||
Rab GDI α Antibody (C-7) Alexa Fluor® 488 | sc-271846 AF488 | 200 µg/ml | $364.00 | |||
Rab GDI α Antibody (C-7) Alexa Fluor® 546 | sc-271846 AF546 | 200 µg/ml | $364.00 | |||
Rab GDI α Antibody (C-7) Alexa Fluor® 594 | sc-271846 AF594 | 200 µg/ml | $364.00 | |||
Rab GDI α Antibody (C-7) Alexa Fluor® 647 | sc-271846 AF647 | 200 µg/ml | $364.00 | |||
Rab GDI α Antibody (C-7) Alexa Fluor® 680 | sc-271846 AF680 | 200 µg/ml | $364.00 | |||
Rab GDI α Antibody (C-7) Alexa Fluor® 790 | sc-271846 AF790 | 200 µg/ml | $364.00 | |||
Rab GDI α (C-7) Neutralizing Peptide | sc-271846 P | 100 µg/0.5 ml | $69.00 |