Rab 4A Antibody (E-10): sc-515773

Rab 4A Antibody (E-10) is a mouse monoclonal IgG2b antibody that detects Rab 4A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rab 4A plays a crucial role in the regulation of endosomal trafficking, particularly in the recycling of membrane proteins back to the plasma membrane, which is essential for maintaining cellular homeostasis and signaling. Rab 4A is primarily located in the cytoplasm and is associated with early endosomes, where Rab 4A facilitates the transport of vesicles containing proteins that need to be recycled. The proper functioning of Rab 4A is vital, as disruptions in Rab 4A activity can lead to impaired cellular communication and contribute to various diseases, including neurodegenerative disorders. Rab 4A interacts with several effector proteins, including the exocyst complex, which is involved in the docking and fusion of vesicles with the plasma membrane, further underscoring Rab 4A importance in vesicular transport processes. Anti-Rab 4A antibody (E-10) enables researchers to gain valuable insights into the dynamics of intracellular trafficking and the role of Rab proteins in cellular function.

The preferred Rab 4/14 antibody is Rab 4/14 Antibody (F-10): sc-376243.