Rab 34 Antibody (E-10): sc-373976
- Rab 34 Antibody (E-10) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 213-257 mapping near the C-terminus of Rab 34 of human origin
- recommended for detection of Rab 34 of human origin by WB, IP, IF and ELISA
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Rab 34 Antibody (E-10) for WB applications. These reagents are now offered in bundles with Rab 34 Antibody (E-10) (see ordering information below).
Rab 34 Antibody (E-10) is a mouse monoclonal IgG2a antibody that detects Rab 34 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rab 34 is a member of the Rab family of small GTPases, which play a crucial role in intracellular membrane trafficking and vesicle transport. Specifically, Rab 34 is localized to the Golgi apparatus and is involved in the regulation of vesicle transport from the Golgi to the plasma membrane, a process essential for maintaining cellular homeostasis and facilitating communication between cells. Proper functioning of Rab 34 is vital, as disruptions in activity can lead to various cellular dysfunctions and are implicated in diseases such as cancer and neurodegenerative disorders. Additionally, Rab proteins, including Rab 34, undergo post-translational modifications such as prenylation, which are critical for membrane association and functional activity. Rab 34′s ability to interact with specific effector proteins further underscores its importance in the vesicular transport process, making anti-Rab 34 antibody (E-10) an invaluable tool for researchers studying membrane dynamics and related cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Rab 34 Antibody (E-10) References:
- Rab39, a novel Golgi-associated Rab GTPase from human dendritic cells involved in cellular endocytosis. | Chen, T., et al. 2003. Biochem Biophys Res Commun. 303: 1114-20. PMID: 12684051
- The reticular-activating hypofrontality (RAH) model of acute exercise. | Dietrich, A. and Audiffren, M. 2011. Neurosci Biobehav Rev. 35: 1305-25. PMID: 21315758
- Small GTPase Rab39A interacts with UACA and regulates the retinoic acid-induced neurite morphology of Neuro2A cells. | Mori, Y., et al. 2013. Biochem Biophys Res Commun. 435: 113-9. PMID: 23624502
- Staccato/Unc-13-4 controls secretory lysosome-mediated lumen fusion during epithelial tube anastomosis. | Caviglia, S., et al. 2016. Nat Cell Biol. 18: 727-39. PMID: 27323327
- C9ORF72 is a GDP/GTP exchange factor for Rab8 and Rab39 and regulates autophagy. | Corbier, C. and Sellier, C. 2017. Small GTPases. 8: 181-186. PMID: 27494456
- Rab39a and Rab39b Display Different Intracellular Distribution and Function in Sphingolipids and Phospholipids Transport. | Gambarte Tudela, J., et al. 2019. Int J Mol Sci. 20: PMID: 30987349
- Drosophila Rab39 Attenuates Lysosomal Degradation. | Lakatos, Z., et al. 2021. Int J Mol Sci. 22: PMID: 34638976
- Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells. | Matsui, T., et al. 2022. Cell Rep. 39: 110875. PMID: 35649370
- What is resistant arterial hypertension? | Shalaeva, EV. and Messerli, FH. 2023. Blood Press. 32: 2185457. PMID: 36891929
- A Rab39-Klp98A-Rab35 endocytic recycling pathway is essential for rapid Golgi-dependent furrow ingression. | Miao, H., et al. 2023. Development. 150: PMID: 37590130
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rab 34 Antibody (E-10) | sc-373976 | 200 µg/ml | $316.00 | |||
Rab 34 Antibody (E-10): m-IgGκ BP-HRP Bundle | sc-535355 | 200 µg Ab; 40 µg BP | $354.00 | |||
Rab 34 Antibody (E-10): m-IgG2a BP-HRP Bundle | sc-546224 | 200 µg Ab; 10 µg BP | $354.00 |