PTPN13LY Antibody (H-9): sc-373748
- PTPN13LY Antibody (H-9) is a mouse monoclonal IgG1 κ PTPN13LY antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 3-31 near the N-terminus of PTPN13LY of human origin
- PTPN13LY Antibody (H-9) is recommended for detection of PTPN13LY of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-PTPN13LY Antibody (H-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PTPN13LY Antibody (H-9) for WB and IHC(P) applications. These reagents are now offered in bundles with PTPN13LY Antibody (H-9) (see ordering information below).
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PTPN13LY Antibody (H-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects PTPN13LY protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-PTPN13LY antibody (H-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PTPN13LY protein, also known as PRY, PTPN13LY2, or PRY2, is a 147 amino acid protein that plays a crucial role in cellular signaling pathways, particularly in the testis, where PTPN13LY may function similarly to other protein tyrosine phosphatases. PTPN13LY localization in the testis suggests a specialized role in male reproductive biology and development. PTPN13LY is encoded by a gene located on the Y chromosome, which is essential for male sex determination and development. The Y chromosome contains approximately 58 million base pairs and houses over 80 genes, many of which are critical for proper sexual development. Deletions or defects in Y chromosome-encoded genes can severely impact masculine development and function, highlighting PTPN13LY′s importance in maintaining male reproductive health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PTPN13LY Antibody (H-9) References:
- Characterization of the genomic organization, localization and expression of four PRY genes (PRY1, PRY2, PRY3 and PRY4). | Stouffs, K., et al. 2001. Mol Hum Reprod. 7: 603-10. PMID: 11420382
- The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. | Skaletsky, H., et al. 2003. Nature. 423: 825-37. PMID: 12815422
- A family of human Y chromosomes has dispersed throughout northern Eurasia despite a 1.8-Mb deletion in the azoospermia factor c region. | Repping, S., et al. 2004. Genomics. 83: 1046-52. PMID: 15177557
- Sex determination and gonadal development in mammals. | Wilhelm, D., et al. 2007. Physiol Rev. 87: 1-28. PMID: 17237341
- Mammalian sex--Origin and evolution of the Y chromosome and SRY. | Waters, PD., et al. 2007. Semin Cell Dev Biol. 18: 389-400. PMID: 17400006
- Genetic risk factors in male infertility. | Krausz, C. and Giachini, C. 2007. Arch Androl. 53: 125-33. PMID: 17612870
- Functional coherence of the human Y chromosome. | Lahn, BT. and Page, DC. 1997. Science. 278: 675-80. PMID: 9381176
- A long-range restriction map of deletion interval 6 of the human Y chromosome: a region frequently deleted in azoospermic males. | Yen, PH. 1998. Genomics. 54: 5-12. PMID: 9806824
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PTPN13LY Antibody (H-9) | sc-373748 | 200 µg/ml | $316.00 | |||
PTPN13LY Antibody (H-9): m-IgG Fc BP-HRP Bundle | sc-529549 | 200 µg Ab; 10 µg BP | $354.00 | |||
PTPN13LY Antibody (H-9): m-IgGκ BP-HRP Bundle | sc-522482 | 200 µg Ab, 40 µg BP | $354.00 | |||
PTPN13LY Antibody (H-9): m-IgG1 BP-HRP Bundle | sc-543574 | 200 µg Ab; 20 µg BP | $354.00 | |||
PTPN13LY Antibody (H-9) AC | sc-373748 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PTPN13LY Antibody (H-9) HRP | sc-373748 HRP | 200 µg/ml | $316.00 | |||
PTPN13LY Antibody (H-9) FITC | sc-373748 FITC | 200 µg/ml | $330.00 | |||
PTPN13LY Antibody (H-9) PE | sc-373748 PE | 200 µg/ml | $343.00 | |||
PTPN13LY Antibody (H-9) Alexa Fluor® 488 | sc-373748 AF488 | 200 µg/ml | $357.00 | |||
PTPN13LY Antibody (H-9) Alexa Fluor® 546 | sc-373748 AF546 | 200 µg/ml | $357.00 | |||
PTPN13LY Antibody (H-9) Alexa Fluor® 594 | sc-373748 AF594 | 200 µg/ml | $357.00 | |||
PTPN13LY Antibody (H-9) Alexa Fluor® 647 | sc-373748 AF647 | 200 µg/ml | $357.00 | |||
PTPN13LY Antibody (H-9) Alexa Fluor® 680 | sc-373748 AF680 | 200 µg/ml | $357.00 | |||
PTPN13LY Antibody (H-9) Alexa Fluor® 790 | sc-373748 AF790 | 200 µg/ml | $357.00 | |||
PTPN13LY (H-9) Neutralizing Peptide | sc-373748 P | 100 µg/0.5 ml | $68.00 |